Actively Recruiting
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
Led by University of California, San Diego · Updated on 2026-02-09
250
Participants Needed
2
Research Sites
224 weeks
Total Duration
On this page
Sponsors
U
University of California, San Diego
Lead Sponsor
F
Family Health Centers of San Diego
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized clinical trial is to determine whether a community health worker-delivered, multi-component behavioral intervention can improve antihypertensive medication adherence and blood pressure control among adult refugees with hypertension who are prescribed antihypertensive medications. The main questions it aims to answer are: 1. Does participation in the BPCARE intervention improve antihypertensive medication adherence compared to enhanced usual care? 2. Does participation in the BPCARE intervention improve blood pressure control and persistence over time compared to enhanced usual care? Researchers will compare participants randomized to the BPCARE intervention to those receiving enhanced usual care (hypertension information and a home blood pressure monitor) to determine the effects on medication adherence, blood pressure control, and persistence. Participants will: * Be randomly assigned to either the BPCARE intervention or enhanced usual care * Receive hypertension education and a home blood pressure monitor * Participate in community health worker-delivered sessions that include hypertension and medication education, motivational interviewing, problem-solving, and action planning (intervention arm only) * Complete questionnaires assessing medication adherence and related psychosocial factors * Have blood pressure monitored using connected home blood pressure devices * Complete pill counts to assess medication adherence over a nine-month follow-up period
CONDITIONS
Official Title
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a clinical diagnosis of hypertension determined at screening
- Be at least 21 years of age
- English as a second language
- Be able to provide written informed consent and participate in study procedures
- Have at least one recorded automated clinic systolic blood pressure reading of 130 mmHg or higher within the past year OR at least one home systolic blood pressure reading of 140 mmHg or higher in the last year
- Will not move out of San Diego in the next 6 months
- Have access to a mobile phone or computer with video telecommunication capacity (e.g., Zoom)
You will not qualify if you...
- A cardiovascular event or hospitalization for unstable angina within the last 3 months
- Symptomatic heart failure within the past 6 months or left ventricular ejection fraction less than 35%
- Pregnant or planning on becoming pregnant within the next 7 months
- Current participation in another clinical trial involving medications that may change blood pressure
- Major conditions likely to limit understanding or adherence, such as dementia or psychotic disorders, or inability to conduct pill counts
- Immediate family members already participating in the trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of California, San Diego
San Diego, California, United States, 92093
Active, Not Recruiting
2
Family Health Centers of San Diego
San Diego, California, United States, 92102
Actively Recruiting
Research Team
T
Tala Al-Rousan, MD, MPH
CONTACT
S
Sabrina Smadi, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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