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Actively Recruiting

Age: 16Years - 99Years
All Genders
ID06220448

Study of Blunt Adrenal Gland Injury in Adults With Thoraco-Abdominal Trauma and Its Impact on Trauma Severity and Outcomes

Led by Niguarda Hospital · Updated on 2026-04-16

5000

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating blunt adrenal gland injury BAGI, a rare condition occurring after blunt thoraco-abdominal trauma. This observational multicenter study focuses on adult patients who have undergone either non-operative or operative management. The study aims to clarify the conflicting reports about BAGIs impact on trauma severity and patient outcomes, and to explore whether the injurys anatomical location or other physiological factors influence these outcomes. The study collects data from multiple institutions by reviewing medical records of patients with blunt thoraco-abdominal trauma, comparing those with BAGI to those without. Key information includes demographics, trauma mechanism, treatment details, trauma severity scores, ventilation needs, vasoactive support, clinical and laboratory parameters, mortality, and hospital stays. Data analysis will follow established observational study guidelines and use statistical matching to fairly compare the two patient groups. Participants will have their information gathered retrospectively from trauma registries, with personal data anonymized. The study measures injury severity scores, organ injury scales, survival rates, length of hospital and ICU stays over a 120-day period after trauma. This comprehensive evaluation helps understand the burden of BAGI among major trauma patients and aims to improve knowledge about this injurys clinical implications.

CONDITIONS

Brief Title

Blunt ADrenal Gland injUrY (BAD GUY) Project

Who Can Participate

Age: 16Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 16 years old
  • Patients with blunt thoraco-abdominal trauma
Not Eligible

You will not qualify if you...

  • Traumatic brain injury with a severity score greater than 3
  • Isolated traumatic brain injury and spinal cord injury
  • Patients who died in the emergency department

Research Team

S

Stefano P Cioffi, MD

L

Laura Benuzzi, MD

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