Actively Recruiting

Phase Not Applicable
Age: 45Years - 75Years
All Genders
NCT04716803

Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

Led by University of California, San Diego · Updated on 2022-01-26

10

Participants Needed

1

Research Sites

181 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to investigate the safety and effectiveness of bone marrow aspirate concentrate (BMAC) in patients with moderate to severe osteoarthritis of the knee. BMAC provides a rich source of mesenchymal stem cells (MSCs) and is a stem cell-based therapy that has been reported to preserve or improve the structure of joints. The Angel System is the device used in this study to concentrate bone marrow from the patient and is intended to separate a mixture of blood and bone marrow and collect plasma rich platelets preoperative to a surgical procedure. The goal of this study is to identify whether BMAC can be an effective and safe treatment for patients with osteoarthritis of the knee.

CONDITIONS

Official Title

Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

Who Can Participate

Age: 45Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Kellgren Lawrence radiographic grade IV
  • Recommended total knee arthroscopy by primary care provider or orthopedist
  • Persistent knee pain unresponsive to standard treatments including acetaminophen, non-steroidal anti-inflammatory drugs, physical therapy, intraarticular corticosteroids, or hyaluronic acid
  • Male or female aged 45 to 75 years
Not Eligible

You will not qualify if you...

  • None specified

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California San Diego Koman Outpatient Pavilion

La Jolla, California, United States, 92037

Actively Recruiting

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Research Team

K

Kenneth Kalunian, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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