Actively Recruiting
Pilot Investigation on the Effects of Sub Acute (12 Week) Home Base Whole-body Vibration Training in Osteoarthritis
Led by Augusta University · Updated on 2026-05-14
30
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how the Vibrant Health Ultimate whole-body vibration (WBV) machine affects pain and inflammation in older adults with knee osteoarthritis. The study aims to see if 12 weeks of WBV can reduce knee pain and improve vascular health by lowering systemic inflammation. This approach is being explored as a potentially easier alternative to traditional exercises like walking or cycling for people with knee osteoarthritis. Participants will receive a personal vibration plate with stabilizing bars to use at home for up to 12 weeks. They will stand barefoot on the plate in a specific stance and perform sessions starting with 5-10 minutes per day, 4-5 days per week during the first four weeks. The duration may increase to 15 minutes starting week 5 and up to 20 minutes from week 9, depending on how the participant feels, with rest days recommended between sessions early on. During the study, researchers will measure changes in pain sensitivity using a pain pressure threshold device before and after the 12-week training. They will also assess vascular function through pulse wave velocity and measure inflammation levels by testing IL-6 in the blood. Participants will be monitored throughout, and the study will last for the full 12-week intervention period.
CONDITIONS
Brief Title
Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic osteoarthritic knee pain for at least 6 months
- Men and women
- Ages 40 to 75 years old
You will not qualify if you...
- Younger than 40 years old or older than 75 years old
- History of balance issues
- History of falls
- Epilepsy
- Pregnancy
- Use of whole-body vibration in the past 6 months
- Previous knee surgery within the last 3 years
- Unable to stand for at least 20 minutes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 12 weeks
Participants will use a personal vibration plate at home for whole-body vibration training. Training lasts up to 12 weeks with gradually increasing session times from 5-10 minutes daily to up to 20 minutes, performed 4-5 days per week.
Baseline visit and periodic follow-up visits
Trial Site Locations
Total: 1 location
1
Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology
Augusta, Georgia, United States, 30912
Actively Recruiting
Research Team
J
Jacob Looney, MS
R
Ryan Harris, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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