Actively Recruiting

Age: 5Years +
All Genders
NCT07390318

Bowel Continence Across the Lifespan in People With Spina Bifida

Led by David Chu · Updated on 2026-04-21

943

Participants Needed

24

Research Sites

213 weeks

Total Duration

On this page

Sponsors

D

David Chu

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are: 1. How well do different enema programs prevent bowel accidents? 2. How do these enema programs affect independence, bowel symptoms, and quality of life? Researchers will compare two types of enema programs to see which works better and is easier for participants to manage. Participants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.

CONDITIONS

Official Title

Bowel Continence Across the Lifespan in People With Spina Bifida

Who Can Participate

Age: 5Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Minimum age 5 years old
  • Diagnosis of myelomeningocele
  • Starting or switching to a retrograde or antegrade enema program
  • Able to read and speak English or Spanish
Not Eligible

You will not qualify if you...

  • Having other types of spinal dysraphism such as lipomyelomeningocele or fatty filum

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 24 locations

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35205

Actively Recruiting

2

Children's of Alabama

Birmingham, Alabama, United States, 35233

Actively Recruiting

3

Phoenix Children's Hospital

Phoenix, Arizona, United States, 85006

Actively Recruiting

4

Children's Hospital of Los Angeles

Los Angeles, California, United States, 90027

Actively Recruiting

5

University of California San Francisco

San Francisco, California, United States, 94158

Actively Recruiting

6

Children's Hospital of Colorado

Denver, Colorado, United States, 80218

Actively Recruiting

7

Children's National Hospital

Washington D.C., District of Columbia, United States, 20010

Not Yet Recruiting

8

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611

Actively Recruiting

9

Northwestern University

Chicago, Illinois, United States, 60611

Actively Recruiting

10

Riley Children's Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

11

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

12

University of Michigan

Ann Arbor, Michigan, United States, 48109

Not Yet Recruiting

13

Duke University Medical Center

Durham, North Carolina, United States, 27705

Actively Recruiting

14

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States, 45229

Actively Recruiting

15

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Not Yet Recruiting

16

Nationwide Children's Hospital

Columbus, Ohio, United States, 43205

Actively Recruiting

17

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19139

Actively Recruiting

18

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15224

Actively Recruiting

19

Monroe Carell Jr. Children's Hospital at Vanderbilt

Nashville, Tennessee, United States, 37232

Actively Recruiting

20

Scottish Rite for Children

Dallas, Texas, United States, 75219

Not Yet Recruiting

21

Texas Children's Hospital

Houston, Texas, United States, 77030

Actively Recruiting

22

Primary Children's Hospital

Salt Lake City, Utah, United States, 84113

Not Yet Recruiting

23

Seattle Children's Hospital

Seattle, Washington, United States, 98105

Actively Recruiting

24

University of Washington

Seattle, Washington, United States, 98195

Actively Recruiting

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Research Team

J

Josephine Hirsch

CONTACT

I

Ilina Rosoklija

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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