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Studying Brain, Psychological, and Epigenetic Factors to Improve Treatment for Adults with Chronic Low Back Pain
Led by Université de Sherbrooke · Updated on 2023-09-13
80
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Chronic low back pain CLBP affects many people and can be caused by various arthritis conditions. Researchers aim to better understand how the brain contributes to CLBP by studying its structure and function. This observational study seeks to improve diagnosis and treatment by exploring brain properties and psychological and epigenetic factors in people with CLBP. Participants are individuals living with CLBP who will undergo facet thermal ablation treatment. The study does not provide any intervention itself but observes changes before and after the treatment. Brain scans and other assessments will be conducted at multiple time points 1 week, 2 months, and 4 months before treatment, as well as 2 months and 4 months after treatment. During the study, participants will have brain imaging to measure grey matter volume, blood-oxygen levels, and white matter properties, along with assessments of brain arteries and veins. Researchers will also track changes in pain severity, psychological scores, functional abilities, and other health measures over time. These evaluations help to understand treatment effects on brain and pain-related factors. The study period spans several months with scheduled monitoring before and after treatment.
CONDITIONS
Brief Title
Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
Research Team
P
Pascal Tétreault, PhD
M
Marylie Martel, PhD
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