Brazilian Registry to Study Chronic Non-Communicable Diseases and Mental Health in Adults Living with HIVAIDS

What this Trial Is About

Researchers are conducting the BRAVO study, a multicenter observational research project focused on adults aged 18 and over living with HIVAIDS across Brazil. The study aims to gather detailed information about chronic non-communicable diseases NCDs, mental health, and quality of life in this population to help develop better health policies. It includes participants from various regions in Brazil and emphasizes the importance of understanding cardiometabolic health, mental health, and other risk factors among people living with HIVAIDS. The study collects a wide range of data including sociodemographic details, risk factors for main NCDs, physical examination results, and biological samples for biochemical and metabolic testing. It uses validated tools and some project-developed questionnaires to assess conditions such as depression, anxiety, substance use, and quality of life through the WHOQOL-BREF survey. Data are managed using REDCap software and cover clinical lab tests, physical measures, respiratory function, renal, hepatic, and bone health, as well as sexually transmitted infections and cancer risk assessments. Participants will provide informed consent and undergo a cross-sectional baseline assessment during 2025 and 2026. Researchers will measure the prevalence of chronic diseases, mental disorders, metabolic and behavioral risk factors, antiretroviral therapy adherence, and quality of life at baseline and one year later. The study plans subgroup analyses for specific populations and ensures confidentiality and ethical compliance. Participation involves data collection through questionnaires, exams, and sample collection, with a target of 743 participants to ensure reliable results.

BRAZILIAN REGISTRY OF CHRONIC NON-COMMUNICABLE DISEASES IN PEOPLE LIVING WITH HIV/AIDS