Study on How Breastfeeding Affects Childrens Gut Health Tracking Newborns for Four Years

What this Trial Is About

Researchers are investigating how early nutrition affects gut health in children by following a group of newborns from birth up to 4 years old. The study aims to understand how breastfeeding and other feeding practices influence gut health, focusing on measuring fecal secretory immunoglobulin A SIgA and digestive symptoms. The study is observational and sponsored by the University Hospital, Lille. Participants include newborns whose parents provide information about their nutritional habits, breastfeeding duration, and complementary feeding. Biological samples such as cord blood cells and stool are collected at birth, 6 months, 2 years, and 4 years to build a biological collection. The study observes gut health over time and its relationship to early nutrition. During the study, children are regularly assessed for gut health markers and digestive symptoms. Researchers collect data on breastfeeding practices and maternal diet during pregnancy, as well as child growth and gastrointestinal issues. The primary outcome is the correlation between exclusive breastfeeding and gut health measured by fecal SIgA at 4 years. Secondary outcomes include correlations between gut health and breastfeeding duration, maternal feeding habits, and child growth. Participation lasts up to 4 years with multiple follow-up visits and sample collections.

Breastfeeding and Gut Health