Study of Brain Stimulation and Breathing Tasks to Prevent Seizure-Related Breathing Failure in Adults with Focal Epilepsy

What this Trial Is About

Researchers are studying people with focal epilepsy to better understand the brain networks that control breathing and to find brain areas and stimulation methods that might help prevent breathing failure caused by seizures. This study aims to identify precise brain functions related to respiration using electrical stimulation techniques. Participants will perform various breathing tasks such as normal breathing through the nose or mouth, breathing while resting, changing their breathing rate, and breath counting. Brain mapping will be done using electrical stimulation with specialized equipment to locate areas involved in breathing. This procedure uses a neural function measuring system with a brain stimulation device during the hospital stay. During the study, researchers will monitor breathing changes using EEG signals, thoracoabdominal belts, nasaloral pressure sensors, pulse oximetry, and carbon dioxide measurements before and during stimulation sessions. They will measure changes in breathing rate, depth, and minute ventilation. The study involves an inpatient stay in an epilepsy monitoring unit where participants undergo brain recording and stimulation to assess outcomes related to breathing function.

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