Actively Recruiting

Age: 18Years +
All Genders
NCT06702059

Cardiopulmonary Exercise Testing in Cardiosurgery Patients

Led by St. Anne's University Hospital Brno, Czech Republic · Updated on 2025-05-15

130

Participants Needed

2

Research Sites

173 weeks

Total Duration

On this page

Sponsors

S

St. Anne's University Hospital Brno, Czech Republic

Lead Sponsor

C

Centre of Cardiovascular and Transplantation Surgery, Czech Republic

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications. Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.

CONDITIONS

Official Title

Cardiopulmonary Exercise Testing in Cardiosurgery Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients scheduled for coronary artery bypass graft surgery
Not Eligible

You will not qualify if you...

  • Unable to perform cardiopulmonary exercise testing
  • Off-pump revascularization
  • Surgery without full sternotomy
  • Previous cardiac surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Centre of Cardiovascular and Transplantation Surgery

Brno, Czech Republic, Czechia, 60200

Actively Recruiting

2

St. Anne's University Hospital in Brno

Brno, Czech Republic, Czechia, 61200

Active, Not Recruiting

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Research Team

I

Ivan Cundrle, prof., M.D.

CONTACT

M

Marek Lukes, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Cardiopulmonary Exercise Testing in Cardiosurgery Patients | DecenTrialz