Actively Recruiting
Cardiopulmonary Exercise Testing in Cardiosurgery Patients
Led by St. Anne's University Hospital Brno, Czech Republic · Updated on 2025-05-15
130
Participants Needed
2
Research Sites
173 weeks
Total Duration
On this page
Sponsors
S
St. Anne's University Hospital Brno, Czech Republic
Lead Sponsor
C
Centre of Cardiovascular and Transplantation Surgery, Czech Republic
Collaborating Sponsor
AI-Summary
What this Trial Is About
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications. Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.
CONDITIONS
Official Title
Cardiopulmonary Exercise Testing in Cardiosurgery Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for coronary artery bypass graft surgery
You will not qualify if you...
- Unable to perform cardiopulmonary exercise testing
- Off-pump revascularization
- Surgery without full sternotomy
- Previous cardiac surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Centre of Cardiovascular and Transplantation Surgery
Brno, Czech Republic, Czechia, 60200
Actively Recruiting
2
St. Anne's University Hospital in Brno
Brno, Czech Republic, Czechia, 61200
Active, Not Recruiting
Research Team
I
Ivan Cundrle, prof., M.D.
CONTACT
M
Marek Lukes, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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