Actively Recruiting

Age: 18Years +
All Genders
NCT06344650

Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess.

Led by IRCCS San Raffaele · Updated on 2024-08-22

100

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

Sponsors

I

IRCCS San Raffaele

Lead Sponsor

F

Fondazione Policlinico Universitario Campus Bio-Medico

Collaborating Sponsor

AI-Summary

What this Trial Is About

Prospective observational clinical, molecular, translational study aimed at identifying the main determinants and predictive factors of fragility fracture risck in acromegaly patients

CONDITIONS

Official Title

Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of acromegaly
  • Availability to carry out outpatient checks
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Use of glucocorticoids (except those in use for replacement therapy)
  • Alcohol abuse
  • Exacerbation of chronic disease
  • Serious comorbidities such as renal or hepatic failure, heart attack, stroke
  • Terminal illness or prolonged immobilization (more than 1 week)
  • Clinically evident fracture within the previous six months
  • Any other cause of secondary osteoporosis within the last five years
  • Prolonged treatment with drugs affecting bone metabolism during the past 12 months, including antiresorptive or anabolic compounds for osteoporosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Andrea Giustina

Milan, Italy, 20132

Actively Recruiting

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Research Team

S

Stefano Frara, MD

CONTACT

G

Gabriela Felipe, Nurse

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess. | DecenTrialz