Migraine, headache disorders, and brain health: aligning advocacy with the UN Sustainable Development Goals.
Paolo Martelletti, Arão Belitardo de Oliveira, Rajinder K Dhamija...
https://pubmed.ncbi.nlm.nih.gov/41947032Actively Recruiting
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID07554664
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine: A Cross-Sectional Study
Led by Bozok University · Updated on 2026-05-19
159
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Migraine is a widespread neurological condition that causes significant disability, especially among working-age individuals. It is characterized by increased sensitivity in the nervous system, leading to heightened pain and associated symptoms such as neck and musculoskeletal pain. This research aims to compare central sensitization, work-related stress, and musculoskeletal symptoms in desk-based workers with and without migraine, addressing a gap in understanding how these factors interact in this population. The study involves participants who work at desks for at least four hours daily and categorizes them into groups with episodic migraine, chronic migraine, or no migraine diagnosis. It evaluates their central sensitization using the Central Sensitization Inventory and measures headache intensity, disability, work stress, musculoskeletal pain symptoms, and headache impact. The study is observational and collects data at a single point in time. Participants will undergo demographic and clinical evaluations along with completing questionnaires related to their symptoms and stress levels. The primary outcome is the Central Sensitization Inventory score collected on the first day. Secondary outcomes include assessments of headache impact, disability, and musculoskeletal symptoms. The study helps to understand the relationships among migraine, musculoskeletal pain, and work stress in desk-based workers and is led by Bozok University.
CONDITIONS
Brief Title
Central Sensitization, Work-Related Stress, and Musculoskeletal Symptoms in Desk-Based Workers With and Without Migraine
Who Can Participate
Age: 18Years - 65Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Employed in an office job for at least 6 months
- Working at a desk for at least 4 hours a day
- Able to read and understand Turkish
- Agreeing to participate voluntarily
- For migraine group: diagnosed with episodic or chronic migraine according to International Classification of Headache Disorders Edition 3
- For control group: no diagnosis of migraine or other primary headache
You will not qualify if you...
- History of neurological disorders such as Multiple Sclerosis
- Inflammatory rheumatic disorders like Rheumatoid Arthritis
- Chronic pain syndromes such as Fibromyalgia
- Any other headache disease besides migraine
- Any systemic disease
- Recent acute fracture or infection
- Neck or spinal surgery within the last 6 months
- Serious musculoskeletal trauma within the last 6 months
- Pregnancy
- Cognitive or psychiatric conditions preventing questionnaire completion
- For control group: history of recurrent headaches in the past year
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - 1 day
Participants complete assessments to evaluate central sensitization, headache characteristics, work-related stress, musculoskeletal symptoms, and demographic information.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Gaziantep City Hospital
Gaziantep, Merkez, Turkey (Türkiye)
Actively Recruiting
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Research Team
D
Dilara ONAN, PhD
P
Pelin YENİLMEZ YEŞİLDAŞ, Neurologist
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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Chunlin Li, Lei Zhang, Jin Zhou...
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Pierre Côté, Gabrielle van der Velde, J David Cassidy...
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Stefany Lee, Fernanda Cabegi DE Barros, Cristiane Shinohara Moriguchi DE Castro...
https://pubmed.ncbi.nlm.nih.gov/33250456Work-related Neck Pain Among Desk Job Workers of Tertiary Care Hospital in New Delhi, India: Burden and Determinants.
Surendra Babu Darivemula, Kiran Goswami, Sanjeev Kumar Gupta...
https://pubmed.ncbi.nlm.nih.gov/26917874