Clinical Outcomes and Valve Performance After Transcatheter Aortic Valve Replacement in Adults with Severe Aortic Valve Disease

What this Trial Is About

Researchers are analyzing clinical outcomes and valve performance in adults who underwent transcatheter aortic valve replacement TAVR for severe aortic valve disease. This multicenter, retrospective observational study uses data from the CHATEAU Registry, focusing on procedural strategies, valve-related factors, and long-term results in routine medical practice between January 2021 and December 2025. The study collects existing medical records including patient information, imaging, procedural details, echocardiographic results, and follow-up outcomes. No new treatments, interventions, or study visits are conducted, as all data come from past clinical care. The study will assess outcomes like mortality, stroke, heart failure hospitalization, valve function, and device-related events up to December 31, 2027. Participants involvement is limited to data collection from their previous clinical records. Researchers will review clinical, imaging, laboratory, and follow-up information to evaluate associations between patient, anatomy, device, and procedural factors with clinical outcomes. No additional procedures or visits are required, and data privacy regulations are followed throughout the study.

CHATEAU Registry: Clinical Outcomes After Transcatheter Aortic Valve Replacement