Actively Recruiting

Age: 1Year - 3Years
All Genders
NCT04529967

Child-Parent Familial Hypercholesterolemia Screening

Led by Children's Hospital of Fudan University · Updated on 2025-05-07

15000

Participants Needed

6

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Child-parent screening for familial hypercholesterolemia has been proposed to identify children and their parent who are carrier of mutations and with high risk for inherited premature coronary artery disease. The investigators assessed the efficacy and feasibility of such screening in primary care practice. key scientific questions: 1. The 95th and 99th percentile of finger blood TC in children of 2 years old. 2. Mutations that contribute to high TC status ( serum TC \>99th percentiles) compared with international FH48 panel for FH genetic screening.

CONDITIONS

Official Title

Child-Parent Familial Hypercholesterolemia Screening

Who Can Participate

Age: 1Year - 3Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Receive routine child care
  • Aged 1 to 3 years old (calculated from date of investigation minus date of birth)
Not Eligible

You will not qualify if you...

  • Participation suitability to be decided by the researcher

AI-Screening

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Trial Site Locations

Total: 6 locations

1

Anhui Provincial Children's Hospital

Hefei, Anhui, China

Actively Recruiting

2

Qidong Women and Children Hospital

Qidong, Jiangsu, China

Actively Recruiting

3

Weili Yan

Shanghai, Shanghai Municipality, China, 201102

Actively Recruiting

4

Shanxi Provincial Children's Hospital

Taiyuan, Shanxi, China

Actively Recruiting

5

Chongqin Medical University Affiliated Children's Hospital

Chongqing, Sichuan, China

Actively Recruiting

6

Urumqi Children's Hospital

Ürümqi, Xinjiang, China, 830000

Actively Recruiting

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Research Team

W

Weili Yan

CONTACT

F

Fang Liu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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