Actively Recruiting
The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
Led by China National Center for Cardiovascular Diseases · Updated on 2018-03-27
3000
Participants Needed
1
Research Sites
927 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiac diseases, with a prevalence of ∼0.2%. Sudden cardiac death (SCD), heart failure and stroke are the major poor outcomes of HCM. Although about half of the patients were found to be caused by mutations mainly located in genes encoding sarcomere proteins, the causes in a significant proportion of patients with HCM are still unknown. Even in the patients with sarcomere mutations, the molecular pathways that eventually lead to cardiac hypertrophy are remained to be revealed. Furthermore, HCM presents with significant heterogeneity. SCD risk stratification and prevention by ICD are necessary. However, the strategy of SCD risk stratification recommended by the 2011 ACCF/AHA and 2014 ESC guidelines were based mainly on the evidence derived from American and European countries. The accuracy of these guidelines in Chines patients with HCM was not evaluated yet.
CONDITIONS
Official Title
The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with hypertrophic cardiomyopathy by unexplained maximal left ventricle wall thickness of 15 mm or more on echocardiography or cardiac MRI
- Or wall thickness of 13 mm or more if there is a family history of hypertrophic cardiomyopathy
You will not qualify if you...
- Presence of other cardiac or systemic diseases that can cause similar heart muscle thickening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai hospital
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
S
Song Lei, MD.&ph.D
CONTACT
S
Song Lei, MD.&ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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