Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06058585

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

Led by The George Institute · Updated on 2026-04-01

1000

Participants Needed

43

Research Sites

238 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

CAPTIVATE is an international, multi-centre, Phase III, adaptive, platform, randomised controlled trial in people with chronic kidney disease (CKD). CAPTIVATE aims to find the best treatment, or combination of treatments, that slow the progression of CKD so that fewer people develop kidney failure. CAPTIVATE provides a research platform that allows many treatment-related questions to be answered within a common trial set-up.

CONDITIONS

Official Title

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 18 years
  • Known chronic kidney disease from any cause with eGFR 65 mL/min/1.73m2
  • Currently receiving standard of care treatment as decided by treating physician
  • Eligible for randomisation in at least one recruiting domain-specific appendix
  • Participant and treating physician willing and able to perform trial procedures
Not Eligible

You will not qualify if you...

  • Planned to start kidney replacement therapy or kidney transplant surgery in the next 6 months
  • Life expectancy less than 6 months

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 43 locations

1

The Canberra Hospital

Garran, Australian Capital Territory, Australia, 2605

Actively Recruiting

2

Nepean Blue Mountains Local Health District

Kingswood, New South Wales, Australia, 2747

Actively Recruiting

3

St George Hospital

Kogarah, New South Wales, Australia, 2217

Actively Recruiting

4

John Hunter Hospital

New Lambton Heights, New South Wales, Australia, 2305

Actively Recruiting

5

Westmead Hospital

Westmead, New South Wales, Australia, 2145

Actively Recruiting

6

Sunshine Coast Hospital and Health Service

Birtinya, Queensland, Australia, 4575

Actively Recruiting

7

Townsville University Hospital

Douglas, Queensland, Australia, 4814

Actively Recruiting

8

West Moreton Hospital & Health Service

Ipswich, Queensland, Australia, 4305

Actively Recruiting

9

Gold Coast Hospital and Health Service

Southport, Queensland, Australia, 4215

Actively Recruiting

10

Royal Adelaide

Adelaide, South Australia, Australia, 5000

Actively Recruiting

11

Lyell McEwin Hospital

Elizabeth Vale, South Australia, Australia, 5112

Actively Recruiting

12

Austin Health

Heidelberg, Victoria, Australia, 3084

Actively Recruiting

13

South Metropolitan Health Service, Fiona Stanley Hospital

Murdoch, Western Australia, Australia, 6150

Actively Recruiting

14

Gitam Institute of Medical Sciences and Research

Visakhapatnam, Andhra Pradesh, India, 530045

Actively Recruiting

15

Patna Medical College and Hospital

Patna, Bihar, India, 800001

Actively Recruiting

16

DKS Super Speciality Hospital, Raipur

Raipur, Chhattisgarh, India, 492002

Actively Recruiting

17

Mysore Medical College

Dehradun, Dehradun, India, 248001

Actively Recruiting

18

GCS Medical College, Hospital & Research Centre

Ahmedabad, Gujarat, India, 380025

Actively Recruiting

19

Father Muller Medical College Hospital

Mangaluru, Karnataka, India, 575002

Actively Recruiting

20

Dr Moopen's Medical College

Meppādi, Kerala, India, 673511

Actively Recruiting

21

CARE-CHL Hospital

Indore, Madhya Pradesh, India

Actively Recruiting

22

Medway Hospital

Chennai, Tamil Nadu, India, 600024

Actively Recruiting

23

Yashoda Hospital Hitec City

Hyderabad, Telangana, India, 500084

Actively Recruiting

24

Apollo Hospitals

Hyderabad, Telangana, India

Actively Recruiting

25

Charak Hospital and Research Centre

Lucknow, Uttar Pradesh, India, 226003

Actively Recruiting

26

Shri Guru Ram Rai Medical College and Shri Mahant Indiresh Hospital

Dehradun, Uttarakhand, India, 248001

Actively Recruiting

27

Fortis Hospital

Kolkata, West Bengal, India, 700107

Actively Recruiting

28

North Bengal Medical College & Hospital

Siliguri, West Bengal, India, 734012

Actively Recruiting

29

Max Superspeciality Hospital, Dehradun

Dehradun, India, 248001

Actively Recruiting

30

Health New Zealand, Te Whatu Ora Te Matau a Maui, Hawke's Bay Hospital

Hastings, Hawkes Bay, New Zealand, 4120

Actively Recruiting

31

Health New Zealand, Te Whatu Ora Waitemata, North Shore Hospital

Auckland, New Zealand, 0620

Actively Recruiting

32

Auckland City Hospital

Auckland, New Zealand, 1023

Actively Recruiting

33

Aotearoa Clinical Trials Trust, Middlemore Hospital

Auckland, New Zealand, 2025

Actively Recruiting

34

201 Great King Street, Central Dunedin, Dunedin 9016, New Zealand

Dunedin, New Zealand, 9016

Actively Recruiting

35

Private Bag 9742 Maunu Road, Horahora, Whangārei 0148, New Zealand

Whangarei, New Zealand, 0148

Actively Recruiting

36

Hospital Clinico Universitario València (INCLIVA)

Valencia, Espana, Spain, 46010

Actively Recruiting

37

National Nephrology Specialized Hospital

Colombo, Polonnaruwa, Sri Lanka, 51000

Actively Recruiting

38

National Hospital of Sri Lanka

Colombo, Sri Lanka, 00700

Actively Recruiting

39

Kandy National Hospital

Kandy, Sri Lanka, 20000

Actively Recruiting

40

Kurunegala Teaching Hospital

Kurunegala, Sri Lanka

Actively Recruiting

41

Sri Jayewardenepura General Hospital

Nugegoda, Sri Lanka, 10250

Actively Recruiting

42

Peradeniya Teaching Hospital

Peradeniya, Sri Lanka, 20400

Actively Recruiting

43

Colombo North Teaching Hospital

Ragama, Sri Lanka, 11010

Actively Recruiting

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Research Team

E

Enmoore Lin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

2

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