Actively Recruiting

Age: 18Years +
All Genders
ID06635590

The Impact of Hyperkalemia-Induced ECG and ECHO Findings on Early and Late Mortality in Patients With Chronic Kidney Disease

Led by Saglik Bilimleri Universitesi · Updated on 2024-10-10

40

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

This research investigates patients with chronic kidney disease (CKD) who have an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m² and present to the emergency department with isolated high potassium levels (hyperkalemia). The study aims to examine electrocardiogram (ECG) and echocardiography (ECHO) findings in these patients and their association with early and late mortality. Researchers will compare these findings to existing literature to better understand the cardiac effects of hyperkalemia in CKD patients. Participants will form a single group of patients diagnosed with hyperkalemia. Blood samples will be taken to measure potassium levels, followed by ECG and ECHO tests before and after treatment. The ECHO is performed by an experienced physician who is not involved in treatment decisions. The study does not interfere with any medical interventions, which remain under the care of the responsible physician. Throughout the study, data from ECG, ECHO, and laboratory tests will be collected and analyzed. Mortality will be tracked at 24 hours, 7 days, and 30 days after enrollment, excluding other causes of death. The main outcome is to observe changes in echocardiographic findings over 30 days. This study also explores the potential link between cardiac imaging changes due to hyperkalemia and patient survival, offering insight into the usefulness of combined ECG and ECHO monitoring.

CONDITIONS

Brief Title

Chronic Kidney Disease, Hyperkalemia and Echocardiographic Changes

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years old
  • Chronic kidney disease with eGFR less than 60 mL/min/1.73 m²
  • Hyperkalemia detected in the emergency department
  • Willingness to participate and sign the consent form
Not Eligible

You will not qualify if you...

  • Patients under 18 years old
  • Patients unwilling to participate
  • Patients without chronic kidney damage
  • Patients without detected hyperkalemia
  • Patients requiring cardiopulmonary resuscitation due to hyperkalemia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 30 days

Participants undergo ECG and echocardiography (ECHO) tests along with blood sampling to measure potassium levels. These assessments are performed before and after treatment to record cardiac function and changes.

1 visit at enrollment and additional visits as needed for post-treatment assessments

Long-term Monitoring

Duration - 30 days

Participants are monitored for mortality outcomes at 24 hours, 7 days, and 30 days after enrollment to evaluate the relationship between ECG and ECHO findings and mortality.

Follow-up contacts or assessments at 24 hours, 7 days, and 30 days

Trial Site Locations

Total: 1 location

1

Etlik City Hospital

Ankara, Turkey (Türkiye), 06170

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Research Team

G

Gulsen AKCAY, Ass. Prof.

E

Emre CAKAR, Resident

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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