Actively Recruiting
Impact of Aerobic Exercises on Serum Uric Acid Levels in Hemodialysis Patients
Led by Cairo University · Updated on 2025-11-19
32
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the effects of aerobic exercise on patients undergoing hemodialysis (HD) who often have high serum uric acid (SUA) levels. These elevated levels are linked to heart problems, joint pain, and reduced quality of life (QoL). This randomized controlled trial aims to evaluate how aerobic exercise influences SUA levels, functional ability, and QoL in HD patients aged 40 to 60 years. Participants will be randomly divided into two groups. Group A will receive a conventional physical therapy program including breathing, stretching, and lower limb circulatory exercises plus a 6-week aerobic exercise regimen performed three times weekly for 20 to 45 minutes per session. Aerobic activities include treadmill walking or stationary biking at moderate intensity. Group B will receive only the conventional physical therapy program without aerobic exercise. During the study, researchers will measure SUA levels using a biochemistry analyzer, assess functional capacity with the Six-Minute Walk Test (6MWT), and evaluate quality of life using the Kidney Disease Quality of Life Short Form (KDQOL-SF™) Arabic Version. These assessments will occur before and after the 6-week intervention to monitor changes. The study provides detailed exercise guidance and aims to understand aerobic exercise's impact on health outcomes in HD patients.
CONDITIONS
Brief Title
Aerobic Exercises and Hemodialysis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hemodialysis patients aged 40 to 60 years
- Medically stable and able to participate in physical activity
- Able to understand and follow study commands
- Stable on hemodialysis treatment for at least 3 months
You will not qualify if you...
- Significant cardiovascular or respiratory diseases that limit exercise ability
- Severe cognitive impairment or psychiatric conditions interfering with participation
- Acute medical conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants engage in either a conventional physical therapy program alone or combined with an aerobic exercise program consisting of 3 sessions per week lasting 20 to 45 minutes each, performed on non-dialysis days.
3 sessions per week on non-consecutive days
Trial Site Locations
Total: 1 location
1
Physical Therapy faculty, Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
D
Doaa Rafat Assistant professor of physical therapy - Cairo university
M
Mahetab Gamal Ali
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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