Actively Recruiting

Age: 0Years - 99Years
All Genders
NCT02835911

Clinical Cohort of Lymphoma Patients in Malawi

Led by UNC Lineberger Comprehensive Cancer Center · Updated on 2026-01-06

800

Participants Needed

1

Research Sites

900 weeks

Total Duration

On this page

Sponsors

U

UNC Lineberger Comprehensive Cancer Center

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This registry study is intended to establish a large prospective longitudinal clinical cohort of lymphoma patients in Malawi, as such data is currently lacking from sub-Saharan Africa. The investigators will perform core biopsies on at least 800 consecutively enrolled patients with suspected lymphoma for accurate histopathologic characterization. The investigators will systematically collect relevant clinical and laboratory data, and longitudinally follow those with confirmed hematologic malignancies receiving treatment according to local standards of care to assess outcomes.

CONDITIONS

Official Title

Clinical Cohort of Lymphoma Patients in Malawi

Who Can Participate

Age: 0Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Referred to Kamuzu Central Hospital with suspected lymphoma based on clinical impression
  • Age older than 5 years, or 5 years or younger if lymphoma already confirmed by biopsy
  • No prior or current confirmed cancer diagnosis or cancer treatment
  • Lives within 200 kilometers of Kamuzu Central Hospital
  • Able to understand and comply with study procedures, with help if needed
  • Able to provide written consent in English or Chichewa; consent by patient or guardian
Not Eligible

You will not qualify if you...

  • Does not meet the inclusion criteria listed above
  • Patients may refuse genomic analysis of lymphoma specimens but can still participate

AI-Screening

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Trial Site Locations

Total: 1 location

1

UNC Project

Lilongwe, Malawi

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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