What is the FRAIL+AP program studying for frail older adults?

The FRAIL+AP program is being studied to see if combining a detailed geriatric assessment with a 12-week exercise and education program can improve frailty, physical performance, and reduce falls in adults aged 70 and older. This research aims to develop a practical approach for primary care to support healthier aging.

Who may be eligible for this frailty clinical trial?

Adults aged 70 years or older who live in the community and are frail or pre-frail may be eligible. Participants must be able to provide consent and have medical clearance for low-to-moderate exercise. Severe cognitive or psychiatric disorders may exclude participation. Please review eligibility criteria for more details.

Is there any cost to participate in this frailty clinical trial?

Study-related care, including the exercise program and all trial visits, is provided at no cost. Personal travel expenses may vary and are not guaranteed to be covered.

Actively Recruiting

Phase Not Applicable

Age: 70Years +

All Genders

ID07643064

Evaluating the FRAILAP Program Combining Exercise and Geriatric Assessment to Improve Frailty in Adults Aged 70 and Over

Led by Alberto Bermejo Franco · Updated on 2026-08-07

200

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Frailty is a complex syndrome common among older adults that increases the risk of falls, disability, and other health problems. This research evaluates the FRAILAP program, which combines a Comprehensive Geriatric Assessment with a 12-week multicomponent exercise intervention, including visual-spatial gait retraining using the Tapiz Fisior system. The goal is to see if this approach improves frailty status, physical performance, and functional independence compared to usual care in adults aged 70 and older. The trial involves two groups one receiving the FRAILAP program with supervised and home-based exercise sessions once a week each, plus health education on healthy lifestyles and fall prevention the other group receives standard primary care without the structured exercise program. The intervention lasts 12 weeks and includes exercises focused on strength, balance, mobility, flexibility, and gait retraining. Participants will be assessed at the start and one week after the intervention ends, measuring frailty using the FRAIL Scale and physical performance with the Short Physical Performance Battery. Additional outcomes include falls, pain, mood, functional independence, nutrition, handgrip strength, comorbidities, and healthcare use. The study aims to support healthy aging through a practical program suitable for primary care settings.

CONDITIONS

Brief Title

Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) for Frail Older Adults in Primary Care

Who Can Participate

Age: 70Years +

All Genders

Eligibility Criteria

You may qualify if you...

Community-dwelling adults aged 70 years or older
Ability and willingness to provide written informed consent
Medical clearance to participate in low-to-moderate intensity physical exercise
Presence of frailty or pre-frailty defined by at least two criteria including FRAIL Scale score ≥ 1, SPPB score < 10, gait speed < 0.8 m/s, Timed Up and Go test > 12 seconds
Functional independence sufficient to participate (Barthel Index > 80)
Registered at one of the participating primary care centers

You will not qualify if you...

Absolute contraindications to physical exercise such as recent acute myocardial infarction, unstable angina, severe uncontrolled cardiovascular disease, or severe uncorrected aortic stenosis
Severe cognitive impairment preventing understanding of study procedures or exercise instructions
Severe psychiatric disorders interfering with participation
Absence of a legally authorized representative when required
Severe uncontrolled behavioral disturbances
Any acute or chronic medical condition deemed unsafe by investigators
Failure to attend the initial mandatory health education workshop
Attendance at fewer than 6 of the 12 scheduled supervised exercise sessions
Development of an acute medical condition contraindicating physical activity
Participant withdrawal of informed consent

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Intervention

Duration - 12 weeks

Participants in the intervention group receive a 12-week program including a comprehensive geriatric assessment, health education, and supervised plus home-based multicomponent exercise sessions featuring strength, balance, mobility, flexibility, and visual-spatial gait retraining using the Tapiz Fisior system. The control group receives standard primary care without the structured exercise program.

Weekly supervised and home-based sessions

Assessment

Duration - Up to 1 week after intervention

Participants undergo evaluations at baseline and one week after completing the intervention to measure frailty status, physical performance, falls, pain, mood, functional independence, nutrition, handgrip strength, comorbidities, and healthcare use.

2 visits (baseline and post-intervention)