Actively Recruiting
Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP
Led by Universitas Padjadjaran · Updated on 2025-03-04
17
Participants Needed
1
Research Sites
32 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to know the effect of multicomponent exercise in frail elderly in community to aging hallmarks. The main question\[s\] it aims to answer are: 1. Do global DNA methylation levels change in elderly people in Bandung after receiving modified poco-poco exercise? 2. Do GDF15 levels change in elderly people in Bandung after they are given modified poco-poco exercise? 3. Do lamin A COP levels change in elderly people in Bandung after they are given modified poco-poco exercise? 4. Does the level of frailty in elderly people in Bandung change after they are given modified poco-poco exercise? Participants will be asked to do flexibility, balance, aerobic and strengthening exercise included in poco-poco modified exercise three times a week for 12 weeks
CONDITIONS
Official Title
Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Frailty level is in pre-frailty
- MoCA INA score above 18
- Domicile in Bandung City
- Willing to participate in the study after informed consent
You will not qualify if you...
- Hearing impairment that may prevent receiving verbal instructions
- Uncorrected visual impairment
- Musculoskeletal disorders preventing exercise or measurements
- Receiving other rehabilitation programs
- Post-stroke with average limb muscle strength below three
- Diseases causing cognitive impairment such as Alzheimer's disease, traumatic head injury, Parkinson's disease
- Severe joint diseases like osteoarthritis and rheumatoid arthritis that worsen with exercise
- Severe cardiovascular disease as assessed by a heart and vascular specialist
- Unable to attend exercises regularly
AI-Screening
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Trial Site Locations
Total: 1 location
1
Puskesmas Sekejati
Bandung, West Java, Indonesia, 40287
Actively Recruiting
Research Team
I
Istingadah Desiana, dr, SpKFR, Ger(K), FIPM (USG)
CONTACT
W
William Giovani, dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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