Actively Recruiting
Effect of Modified Poco-Poco Exercise on Frailty Stages and Aging Markers in Elderly Living in Bandung Community
Led by Universitas Padjadjaran · Updated on 2025-03-04
17
Participants Needed
1
Research Sites
6 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how a modified poco-poco exercise affects aging markers and frailty levels in elderly people living in the community. The study focuses on people aged 60 and older in Bandung, Indonesia, investigating changes in global DNA methylation, GDF15 levels, Lamin A COP levels, and the degree of frailty after exercise. Frailty is a common issue in older adults linked to worsening health, and this study explores whether exercise can influence key biological markers related to aging. Participants will engage in a multicomponent exercise program that includes flexibility, balance, aerobic, and muscle-strengthening activities incorporated into a modified poco-poco routine. This exercise will be performed three times a week for 12 weeks. The modified exercise adds muscle strengthening to the traditional poco-poco exercise to better address the needs of frail elderly individuals. Throughout the study, researchers will measure changes in the participants' levels of global DNA methylation, GDF15, Lamin A COP, and frailty at the start and after 12 weeks. Participants will be regularly assessed to track these biological and physical changes. The study is sponsored by Universitas Padjadjaran and aims to help improve health strategies for the elderly community through physical activity.
CONDITIONS
Brief Title
Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Frailty level is in pre-frailty
- MoCA INA score above 18
- Domicile in Bandung City
- Willing to participate in the study after informed consent
You will not qualify if you...
- Hearing impairment that may prevent receiving verbal instructions
- Uncorrected visual impairment
- Musculoskeletal disorders preventing exercise or measurements
- Receiving other rehabilitation programs
- Post-stroke with limb muscle strength below three
- Diseases causing impaired cognition such as Alzheimer's, traumatic head injury, Parkinson's
- Severe joint diseases like osteoarthritis or rheumatoid arthritis that worsen with exercise
- Severe cardiovascular disease as assessed by a heart and vascular specialist
- Unable to attend exercises regularly
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants engage in modified Poco-Poco exercise training consisting of flexibility, aerobic, balance, and strengthening exercises to address frailty.
Exercise sessions 3 times a week
Trial Site Locations
Total: 1 location
1
Puskesmas Sekejati
Bandung, West Java, Indonesia, 40287
Actively Recruiting
Research Team
I
Istingadah Desiana, dr, SpKFR, Ger(K), FIPM (USG)
W
William Giovani, dr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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