Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07463079

Clinical Evaluation of a Soothing Moisturizing Lotion in Individuals With Atopic Eczema

Led by USMARI Research & Innovation Centre · Updated on 2026-03-16

15

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the safety and effectiveness of a moisturizing lotion in improving symptoms of atopic eczema among adults in Malaysia. The study focuses on individuals with mild to moderate eczema and seeks to assess both skin improvements and participant satisfaction after using the lotion. Participants will apply a moisturizing lotion containing Edelweiss extract, Macadamia seed oil, and shea butter adequately during the 4-week study period. Skin assessments will be conducted at the beginning and at week 4 to measure changes in eczema severity and skin dryness. During the study, participants will undergo evaluations using the Eczema Area and Severity Index (EASI), Investigator's Global Assessment (IGA), and Overall Dry Skin (ODS) scores at baseline and week 4. Safety will be monitored by tracking any treatment-emergent adverse events, and participant satisfaction with the lotion will also be measured at the end of the study.

CONDITIONS

Brief Title

Clinical Evaluation of a Soothing Moisturizing Lotion in Individuals With Atopic Eczema

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy Malaysian men and women
  • Age above 18 years old
  • Clinically diagnosed with mild to moderate eczema with Eczema Area and Severity Index (EASI) score between 10 and 20
Not Eligible

You will not qualify if you...

  • History of allergies or adverse reactions to moisturizers or their components
  • History of chronic allergies
  • Pregnant, breastfeeding women, or planning pregnancy during the study period
  • Documented autoimmune diseases
  • Currently undergoing or requiring active drug treatment for atopic dermatitis or eczema
  • Use of medications like corticosteroids, calcineurin inhibitors, or methotrexate within 3 months before and during the study
  • Current participation in another interventional clinical study
  • Presence of other dermatological or systemic disorders that could affect study outcomes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants apply the moisturizing lotion containing Leontopodium alpinum (Edelweiss) extract, Macadamia ternifolia seed oil, and Butyrospermum parkii (shea) butter as instructed.

1 baseline visit and 1 follow-up visit

Trial Site Locations

Total: 1 location

1

USMARI Research & Innovation Centre

Petaling Jaya, Selangor, Malaysia, 47810

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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