Actively Recruiting
Clinical Outcomes for Deep Brain Stimulation for Parkinson Disease, Tremor, and Dystonia
Led by Washington University School of Medicine · Updated on 2019-06-20
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are collecting long-term clinical outcomes of patients who receive deep brain stimulation (DBS) to treat movement disorders such as Parkinson disease, essential tremor, and dystonia. The study is observational and aims to retrospectively compare and track the risks, benefits, and complications associated with this therapy over time. This research is led by Washington University School of Medicine. Participants undergo deep brain stimulation, which involves high-frequency electrical stimulation of deep brain nuclei to manage movement disorders. There are no experimental drug treatments involved, and the study follows patients who have already received DBS to observe their progress and clinical outcomes. During the study, researchers monitor changes in patient movement and function using tools like the Unified Parkinson's Disease Rating Scale (UPDRS), measuring changes at one year after DBS compared to before surgery. The study tracks these outcomes over time to better understand the effects and safety of DBS in this patient population. Participation involves clinical assessments and follow-up evaluations.
CONDITIONS
Brief Title
Clinical Outcomes for Deep Brain Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of levodopa-responsive Parkinson disease OR
- Diagnosis of medically refractory essential tremor OR
- Diagnosis of medically refractory dystonia
You will not qualify if you...
- Dementia with Mattis Dementia Rating Scale score less than 130
- Structural brain abnormalities that prevent intracranial surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Varies based on individual treatment plans
Participants undergo deep brain stimulation, a device-based procedure for treating movement disorders.
Duration - Up to 1 year after device implementation
Participants are monitored to assess outcomes and changes following deep brain stimulation.
Periodic visits during the year after treatment
Trial Site Locations
Total: 1 location
1
Washington University in St Louis
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
M
Mwiza Ushe, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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