Actively Recruiting
Development of a Prospective Clinico-biological Database in Cachexia in Patients With Colon Cancer
Led by Institut du Cancer de Montpellier - Val d'Aurelle · Updated on 2025-02-13
150
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are developing a prospective clinico-biological database focused on cachexia and undernutrition in patients with colon cancer. Cachexia is a serious syndrome marked by rapid, involuntary weight loss affecting fat and muscle tissues, which can contribute to treatment failure and increased mortality. This study aims to improve understanding of cachexia to enhance patient care and survival by integrating nutritional approaches and clinical nutrition advancements. Participants will have blood samples collected at the start of the study and every six months during treatment, alongside standardized clinical data entered into a database. This collection supports future research projects aimed at tailoring management strategies for patients with colon cancer-related cachexia. The study involves patients treated at a regional cancer institute and monitors biological and clinical risk factors over six years. During the study, participants will undergo regular clinical assessments and blood sample collections to track nutritional and metabolic changes. Researchers will measure the number of clinical and biological risk factors for colorectal cancer until the studys completion. This ongoing monitoring will help identify factors influencing treatment response and toxicity. Participation continues for up to six years, allowing long-term data collection and follow-up.
CONDITIONS
Brief Title
A Clinico-biological Database in Cachexia in Patients With Colon Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Treated at the Montpellier Regional Cancer Institute for colon cancer not eligible for surgery
- Undergoing or requiring treatment for colon cancer such as chemotherapy or targeted therapy
- Accepted the research requirements including blood sample collection
- Affiliated with the Social Protection system
- Signed informed consent form
You will not qualify if you...
- Requiring surgery for colon cancer or metastasis
- Having exclusive peritoneal carcinomatosis
- Requiring radiotherapy
- Unable to understand or comply with study instructions due to psychological, family, social, or geographical reasons
- Pregnant or breastfeeding women
- Receiving care in an emergency context
Research Team
J
Jean-Pierre Bleuse, MD
A
Aurore Moussion
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