Actively Recruiting
Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI)
Led by University of Groningen · Updated on 2025-05-20
126
Participants Needed
3
Research Sites
151 weeks
Total Duration
On this page
Sponsors
U
University of Groningen
Lead Sponsor
S
Stichting Cosis
Collaborating Sponsor
AI-Summary
What this Trial Is About
Seven per cent of patients suffering from severe mental illness (SMI) need long-term intensive treatment and support in a clinical setting or sheltered living. These service users often experience problems on multiple domains, such as persistent complaints as a result of medication resistance, physical health problems and self-care, psychosocial and cognitive dysfunctioning. Cognitive remediation (CR) training is a type of training aimed at improving thinking abilities (cognitive functioning) and daily functioning. However, we don't yet know if CR training can also help people with SMI who need supported housing due to their severe cognitive and daily living problems. In this project, we are investigating whether we can improve daily functioning in this group by using a form of CR training that focuses on learning new cognitive skills and how to use these new skills in everyday life. Additionally, we are exploring whether combining CR training with mild brain stimulation (transcranial Direct Current Stimulation) can enhance the effects of CR training.
CONDITIONS
Official Title
Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A psychiatric disorder that requires care or treatment with persistent symptoms
- Severe disabilities in social or societal functioning
- Disabilities result from a psychiatric disorder
- Disabilities have lasted for several years or more
- Coordinated professional care is needed to carry out a treatment plan
- Adults between the age of 18 and 65 years
- Sufficient written and spoken Dutch language skills
You will not qualify if you...
- Previous experience with CIRCuiTS cognitive remediation training
- Presence of metal implants inside the skull or eye
- Severe scalp skin lesions
- History of seizures
- Alcohol or drug abuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Cosis
Assen, Drenthe, Netherlands, 9400 AE
Actively Recruiting
2
Lentis
Zuidlaren, Drenthe, Netherlands, 9470 AC
Actively Recruiting
3
GGZ Friesland
Leeuwarden, Provincie Friesland, Netherlands, 8932 PA
Actively Recruiting
Research Team
L
Lisette van der Meer, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here