Photodocumentation of corneal scarring. Collaborative Longitudinal Evaluation of Keratoconus Study Group.
J T Barr, M O Gordon, K Zadnik...
https://pubmed.ncbi.nlm.nih.gov/8771545Status Unknown
Age: 12Years +
All Genders
ID00000155
The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study
Led by National Eye Institute (NEI) · Updated on 2005-06-24
N/A
Participants Needed
14
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To describe the clinical course of keratoconus and to describe the relationships among its visual and physiological manifestations, including high- and low-contrast visual acuity, corneal curvature, slit lamp biomicroscopic findings, corneal scarring, and quality of life. To identify risk factors and protective factors that influence the severity and progression of keratoconus.
CONDITIONS
Brief Title
The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study
Who Can Participate
Age: 12Years +
All Genders
Eligibility Criteria
You may qualify if you...
Patients with keratoconus were eligible if they were at least 12 years old; had an irregular cornea as determined by keratometry, retinoscopy, or direct ophthalmoscopy in at least one eye; had Vogt's striae, Fleischer's ring, or corneal scarring characteristic of keratoconus in at least one eye; and planned to stay in the area for at least 3 years. They were ineligible if they had bilateral corneal transplants or bilateral nonkeratoconic eye disease (cataract, intraocular lenses, macular disease, or optic nerve disease other than glaucoma).
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 14 locations
1
University of California, Berkeley, School of Optometry
Berkeley, California, United States, 94720-2020
Status Unknown
2
Southern California College of Optometry
Fullerton, California, United States, 92831
Status Unknown
3
Jules Stein Eye Institute, University of California at Los Angeles
Los Angeles, California, United States, 90095-7003
Status Unknown
4
Nova Southeastern University, Health Professions Division, College of Optometry
Fort Lauderdale, Florida, United States, 33328
Status Unknown
5
University of Illinois at Chicago, Department of Ophthalmology and Visual Sciences
Chicago, Illinois, United States, 60612
Status Unknown
6
Indiana University, School of Optometry
Bloomington, Indiana, United States, 47405-3680
Status Unknown
7
University of Missouri-St. Louis, School of Optometry
St Louis, Missouri, United States, 63121
Status Unknown
8
SUNY State College of Optometry
New York, New York, United States, 10036-8003
Status Unknown
9
University Hospitals of Cleveland, Department of Ophthalmology
Cleveland, Ohio, United States, 44106
Status Unknown
10
The Ohio State University, College of Optometry
Columbus, Ohio, United States, 43210-1240
Status Unknown
11
Pennsylvania College of Optometry, The Eye Institute
Philadelphia, Pennsylvania, United States, 19141
Status Unknown
12
Northeastern Eye Institute
Scranton, Pennsylvania, United States, 18503
Status Unknown
13
University of Utah, John Moran Eye Center
Salt Lake City, Utah, United States, 84132
Status Unknown
14
Gundersen Lutheran
La Crosse, Wisconsin, United States, 54601
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Standardized rigid contact lens fitting protocol for keratoconus.
T B Edrington, J T Barr, K Zadnik...
https://pubmed.ncbi.nlm.nih.gov/8807647Feasibility of fitting contact lenses with apical clearance in keratoconus.
R E Gundel, D P Libassi, K Zadnik...
https://pubmed.ncbi.nlm.nih.gov/9002088Biomicroscopic signs and disease severity in keratoconus. Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group.
K Zadnik, J T Barr, M O Gordon...
https://pubmed.ncbi.nlm.nih.gov/8925661