Long-Term Study of Corneal Disease and Treatment Outcomes Including Corneal Ectasia and Keratoconus at University Hospital Carl Gustav Carus Dresden

What this Trial Is About

This research aims to follow patients with corneal diseases, particularly corneal ectasia such as keratoconus, to analyze the quality of surgical treatments and diagnosis over the long term. Keratoconus causes the cornea to become steeper, thinner, and irregular, leading to irreversible vision loss. Surgical interventions like corneal cross-linking are performed if the disease progresses, making long-term monitoring essential to detect early disease changes and confirm treatment stability. Participants may undergo diagnostic tests including corneal topography and tomography for detailed assessment. The study focuses on observing the natural course and treatment outcomes over 15 years, including postoperative follow-ups. Various eye examinations and measurements are performed, such as anterior optical coherence tomography, Scheimpflug-based tomography, biomechanical assessments, optical biometry, confocal microscopy, and endothelium cell counts. During the study, participants will have regular evaluations of their corneal condition and treatment effects. Researchers collect data on factors like age, sex, family history, previous surgeries, and medications. The main outcomes measured are follow-up intervals and postoperative follow-up intervals over 15 years, as well as assessment of treatment quality. Participants can expect ongoing monitoring to understand disease progression and treatment success throughout the study period.

Dresden Corneal Disease and Treatment Study