Actively Recruiting

Age: 6Months - 120Years
All Genders
Healthy Volunteers
ID04956445

Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development

Led by Tulane University · Updated on 2026-05-19

2000

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

T

Tulane University

Lead Sponsor

C

Centers for Disease Control and Prevention

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are conducting an observational study to better understand how SARS-CoV-2 infections develop and affect people over time, including those with other respiratory viruses. The study aims to track virus shedding, immune responses, and long-term health effects known as post-acute sequelae of SARS-CoV-2 (PASC). This includes monitoring antibody responses and identifying factors that influence disease severity and recovery. The research also seeks to help improve screening, treatment, and prevention strategies for COVID-19 and similar infections. Participants include those recently diagnosed with COVID-19 and other respiratory viruses, as well as individuals who may have been exposed and developed antibodies without confirmed diagnosis. The study collects blood and virus samples to analyze viral genetics, immune responses, and inflammatory markers. Two groups are involved: one with active or recent infections, and another with past infections or possible exposure. Consent is obtained verbally or in writing as appropriate. Throughout participation, individuals provide samples and clinical information at multiple time points to assess symptoms and outcomes up to two years after infection. The study measures include severity of COVID-19 cases and onset of post-COVID symptoms at intervals from 3 months to 24 months. Data collected will help identify predictors of long-term effects and support future treatment development. Participants may be monitored for changes in health status and immune responses during the follow-up period.

CONDITIONS

Brief Title

Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development

Who Can Participate

Age: 6Months - 120Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Positive diagnostic test for COVID-19, influenza A or B, non COVID-19 coronavirus, parainfluenza virus, rhinovirus, adenovirus, or metapneumovirus
  • Patient or legally authorized representative has provided verbal consent or signed informed consent (including parental permission and assent if appropriate)
  • Positive COVID-19 test more than 14 days prior, or potential exposure with antibodies against COVID-19 (for Population 2)
Not Eligible

You will not qualify if you...

  • Under 6 months old
  • Anemia with hemoglobin less than 7
  • Platelet count below 80

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or by telephone) for consent and eligibility assessment

Sample Collection

Duration - Up to 2 years

Participants provide blood and other samples to help understand COVID-19 infection, immune response, and potential treatments.

1 to 2 visits depending on participant group and exposure history

Long-term Monitoring

Duration - Up to 2 years

Participants are monitored to determine long-term health impacts and post-COVID symptoms over time.

Periodic visits at 3, 6, 9, 12, 15, 18, 21, and 24 months

Trial Site Locations

Total: 2 locations

1

Tulane University Medical Center

New Orleans, Louisiana, United States, 70112

Actively Recruiting

2

University Medical Center New Orleans

New Orleans, Louisiana, United States, 70112

Actively Recruiting

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Research Team

D

Dahlene Fusco, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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