Actively Recruiting
Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
Led by Matild Keresztes · Updated on 2026-05-22
70
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
M
Matild Keresztes
Lead Sponsor
T
Tîrgu Mureș Emergency Clinical County Hospital, Romania
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether adding a Transversus Abdominis Plane (TAP) block improves pain control and recovery after cesarean section in women. The study aims to compare postoperative pain scores, opioid use within 24 hours, and quality of recovery between patients receiving the TAP block plus standard care and those receiving the traditional pain management regimen. This trial focuses on postoperative acute pain and the effectiveness of different analgesic strategies after cesarean delivery. Participants are randomly assigned to one of two groups. One group receives an ultrasound-guided TAP block with low concentration ropivacaine (0.2%) at a dose of 0.4 ml/kg per side, performed at the end of surgery under spinal anesthesia, plus postoperative ibuprofen and paracetamol with tramadol as needed. The other group receives the hospital's traditional analgesic regimen including metamizole, NSAIDs, paracetamol, and scheduled tramadol. Pain is managed and assessed using a numeric rating scale, with rescue opioid analgesics given if needed. During the study, participants stay in the obstetric intensive care unit for 12 to 24 hours after surgery before moving to the ward. Pain is measured at rest, during movement, breastfeeding, and walking using the Numeric Rating Scale targeting scores of 4 or less. Opioid consumption is recorded for the first 24 hours. At 24 hours post-surgery, participants complete the ObsQoR-11 questionnaire, which evaluates recovery across physical comfort, independence, emotional state, and pain control. Researchers monitor these outcomes to compare the quality of postoperative recovery and opioid needs between the groups.
CONDITIONS
Brief Title
Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant female patient undergoing cesarean section with spinal anesthesia
You will not qualify if you...
- Receiving general anesthesia for cesarean section
- Receiving combined spinal/epidural anesthesia for cesarean section
- Presence of hypertensive emergencies in obstetrics
- Presence of hemorrhagic emergencies in obstetrics
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo cesarean section with spinal anesthesia. The TAP block or traditional analgesia regimen is administered immediately after surgery.
1 visit (in-person)
Duration - First 24 hours after surgery
Participants receive postoperative pain management with either a TAP block using low concentration ropivacaine or traditional analgesia regimen including NSAIDs and opioids as prescribed.
Continuous monitoring during hospitalization (first 12-24 hours in ICU, then transfer to ward)
Duration - Up to 24 hours after surgery
Participants complete pain assessments and recovery questionnaires to evaluate postoperative analgesia effectiveness and quality of recovery.
1 visit to complete recovery questionnaire and pain assessment
Trial Site Locations
Total: 1 location
1
County Emergency Clinical Hospital of Targu Mureș
Târgu Mureş, Mureș County, Romania, 547581
Actively Recruiting
Research Team
M
Matild Keresztes, Medical doctor
J
Janos Szederjesi, MD, PhD Assoc Prof
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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