Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID07604376

Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%

Led by Matild Keresztes · Updated on 2026-05-22

70

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

Sponsors

M

Matild Keresztes

Lead Sponsor

T

Tîrgu Mureș Emergency Clinical County Hospital, Romania

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating whether adding a Transversus Abdominis Plane (TAP) block improves pain control and recovery after cesarean section in women. The study aims to compare postoperative pain scores, opioid use within 24 hours, and quality of recovery between patients receiving the TAP block plus standard care and those receiving the traditional pain management regimen. This trial focuses on postoperative acute pain and the effectiveness of different analgesic strategies after cesarean delivery. Participants are randomly assigned to one of two groups. One group receives an ultrasound-guided TAP block with low concentration ropivacaine (0.2%) at a dose of 0.4 ml/kg per side, performed at the end of surgery under spinal anesthesia, plus postoperative ibuprofen and paracetamol with tramadol as needed. The other group receives the hospital's traditional analgesic regimen including metamizole, NSAIDs, paracetamol, and scheduled tramadol. Pain is managed and assessed using a numeric rating scale, with rescue opioid analgesics given if needed. During the study, participants stay in the obstetric intensive care unit for 12 to 24 hours after surgery before moving to the ward. Pain is measured at rest, during movement, breastfeeding, and walking using the Numeric Rating Scale targeting scores of 4 or less. Opioid consumption is recorded for the first 24 hours. At 24 hours post-surgery, participants complete the ObsQoR-11 questionnaire, which evaluates recovery across physical comfort, independence, emotional state, and pain control. Researchers monitor these outcomes to compare the quality of postoperative recovery and opioid needs between the groups.

CONDITIONS

Brief Title

Comparative Analysis of the Impact of Transversus Abdominis Plane Block on Post-Cesarean Pain Management Using Low Concentration Ropivacaine 0,2%

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant female patient undergoing cesarean section with spinal anesthesia
Not Eligible

You will not qualify if you...

  • Receiving general anesthesia for cesarean section
  • Receiving combined spinal/epidural anesthesia for cesarean section
  • Presence of hypertensive emergencies in obstetrics
  • Presence of hemorrhagic emergencies in obstetrics

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery

Duration - Day of surgery

Participants undergo cesarean section with spinal anesthesia. The TAP block or traditional analgesia regimen is administered immediately after surgery.

1 visit (in-person)

Treatment

Duration - First 24 hours after surgery

Participants receive postoperative pain management with either a TAP block using low concentration ropivacaine or traditional analgesia regimen including NSAIDs and opioids as prescribed.

Continuous monitoring during hospitalization (first 12-24 hours in ICU, then transfer to ward)

Follow-up

Duration - Up to 24 hours after surgery

Participants complete pain assessments and recovery questionnaires to evaluate postoperative analgesia effectiveness and quality of recovery.

1 visit to complete recovery questionnaire and pain assessment

Trial Site Locations

Total: 1 location

1

County Emergency Clinical Hospital of Targu Mureș

Târgu Mureş, Mureș County, Romania, 547581

Actively Recruiting

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Research Team

M

Matild Keresztes, Medical doctor

J

Janos Szederjesi, MD, PhD Assoc Prof

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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