Comparing REVOLVE, LipoGrafter, and Viality Fat Grafting Methods for Breast Reconstruction After Mastectomy

What this Trial Is About

Researchers are evaluating which fat processing method is best for fat graft retention during breast reconstruction after mastectomy. The study compares three techniques the REVOLVE Advanced Adipose System, LipoGrafter, and Viality. These methods are being assessed for their effectiveness and patient satisfaction in a randomized trial. Participants will be assigned to receive one of the three fat grafting techniques during breast reconstruction surgery. The REVOLVE system processes fat by harvesting, filtering, washing, and removing strands before reinjection. LipoGrafter is a closed system designed to minimize contamination and fat cell damage. The Viality method uses a solution to remove impurities from fat through suction. Each technique will be evaluated to determine differences in graft retention and patient outcomes. During the study, participants will have 3D volumetric scans and complete BREAST-Q questionnaires at the start and 90 days after surgery to measure fat retention and satisfaction. Physical exams at 90 days will check for masses, fat necrosis, infection, seroma, and wound healing. The study monitors these outcomes to compare the safety and effectiveness of each fat processing method in breast reconstruction.

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery