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Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients Undergoing Endodontic Treatment: a Clinical Study
Led by Ankara University · Updated on 2026-03-27
60
Participants Needed
2
Research Sites
3 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical study is designed to evaluate postoperative pain experienced by patients undergoing multi-visit endodontic retreatment and to investigate whether the choice of intracanal medicament influences pain levels between treatment sessions. Postoperative pain is a common concern following root canal procedures and may negatively affect patient comfort, treatment satisfaction, and overall perception of dental care. Calcium hydroxide has long been used as a conventional intracanal medicament in endodontic therapy due to its antimicrobial properties. In recent years, bioceramic-based materials such as Bio-C Temp have been introduced as alternative intracanal medicaments, with proposed advantages related to biocompatibility and interaction with dental tissues. However, limited clinical evidence is available regarding their effect on postoperative pain when compared with conventional materials. In this study, patients requiring multi-visit endodontic retreatment will receive either calcium hydroxide or Bio-C Temp as an intracanal medicament between treatment sessions. Pain intensity will be evaluated at specific time points following treatment using standardized pain assessment scales. In addition to pain intensity, the use of analgesic medication will also be recorded. The primary objective of this study is to compare interappointment postoperative pain levels associated with calcium hydroxide and Bio-C Temp. Secondary objectives include evaluating analgesic consumption. By comparing a conventional intracanal medicament with a newer bioceramic-based alternative, this study aims to contribute to a better understanding of how intracanal medicament selection may influence postoperative pain and patient experience during endodontic retreatment. The findings of this study may help clinicians make more informed decisions regarding intracanal medicament selection and improve pain management strategies in endodontic practice.
CONDITIONS
Official Title
Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients Undergoing Endodontic Treatment: a Clinical Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with single-rooted teeth requiring endodontic retreatment.
- Individuals in good general health, classified as ASA Physical Status I.
- Teeth presenting normal anatomical structure and root morphology.
You will not qualify if you...
- Patients who have used antibiotics or analgesic medications within the last month.
- Pregnant individuals and patients with systemic diseases such as chronic illnesses, diabetes mellitus, hypertension.
- Teeth with root fractures or perforations.
- Teeth with complex root canal anatomy, multirooted teeth, or severely curved roots.
- Patients presenting with high baseline pain levels, particularly those with a history of treatment-resistant pain.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Ankara University Faculty of Dentistry
Ankara, Ankara, Turkey (Türkiye), 06100
Actively Recruiting
2
Ankara University Faculty of Dentistry
Ankara, Ankara, Turkey (Türkiye), 06500
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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