Actively Recruiting
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
Led by Chinese University of Hong Kong · Updated on 2024-11-13
120
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
Sponsors
C
Chinese University of Hong Kong
Lead Sponsor
R
Roche Diagnostics GmbH
Collaborating Sponsor
AI-Summary
What this Trial Is About
To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).
CONDITIONS
Official Title
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients hospitalized for heart failure and pleural effusion
- Pleural tapping indicated for pleural fluid analysis
- Aged 18 years old or above
You will not qualify if you...
- History of intrapleural therapy (including talc and fibrinolytic) in the same pleural space
- History of surgical decortication or pleurodesis in the same pleural space
- Thoracic or cardiac surgery on the same side within the past 3 months
- Unable to give informed consent due to refusal or cognitive impairment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Prince of Wales Hospital
Hong Kong, New Territories, Hong Kong, 0000
Actively Recruiting
Research Team
C
Christopher Chan, MBChB
CONTACT
K
Ken KP Chan, MBChB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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