Comparison of Positive Pressure Ventilation Strategies in Young Children Undergoing Laparoscopic Inguinal Hernia Repair With Laryngeal Mask Airway: A Prospective Randomized Study

What this Trial Is About

Researchers are evaluating different methods of positive pressure ventilation in young children undergoing laparoscopic inguinal hernia repair using a laryngeal mask airway. This trial compares volume-controlled ventilation (VCV), pressure-controlled ventilation (PCV), and pressure-controlled volume-guaranteed ventilation (PCV-VG) to understand their effects on airway pressures and ventilation during surgery. The study is sponsored by Beni-Suef University and involves children aged 1 to 5 years. The trial has three groups of pediatric patients receiving different ventilation strategies during anesthesia. The VCV group receives volume-controlled ventilation with a target tidal volume of 7 mL/kg and respiratory rate of 16 breaths/min. The PCV group receives pressure-controlled ventilation with peak inspiratory pressure adjusted to provide 7 mL/kg tidal volume and a respiratory rate of 16 breaths/min, with a peak inspiratory pressure cap at 20 cm H2O. The PCV-VG group receives pressure-controlled volume-guaranteed ventilation with similar tidal volume and breathing rate settings. Participants will be monitored during surgery for airway pressures, lung compliance, airway resistance, tidal volume, carbon dioxide levels, and other respiratory parameters within one hour. Researchers will also observe postoperative respiratory adverse events for 24 hours after surgery. The study includes physical status assessments and will track heart rate and mean arterial pressure during the observation period. Participation lasts from pre-surgery through 24 hours post-operation.

Comparing Different Startegies of Positive Pressure Ventilation in Children