Actively Recruiting
Comparing Glycemic Control Efficacy Between The National Health System and Suez Canal University Protocols of Intravenous Insulin Infusion for Diabetic Adults in ICU
Led by Suez Canal University · Updated on 2025-02-05
100
Participants Needed
1
Research Sites
6 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two protocols for intravenous insulin infusion to improve blood sugar control in diabetic critically ill adults admitted to intensive care units at Suez Canal University (SCU) hospitals. The study aims to find out whether the SCU protocol is more effective than the National Health System (NHS) protocol used in the UK for managing blood glucose levels in these patients. This comparison will help determine the best way to control blood sugar in critically ill diabetic adults. Participants will be randomly assigned to one of two groups: one group will follow the SCU insulin infusion protocol, while the other will follow the NHS protocol. Both groups will receive regular insulin through an intravenous infusion, with doses adjusted according to their assigned protocol and blood sugar levels. Nurses will prepare and monitor the insulin infusion carefully, stopping it if blood sugar falls below 80 mg/dl. Potassium levels will be regularly checked and managed based on specific guidelines during the study. During the study, patients will have routine blood tests, including daily checks and more frequent potassium monitoring if needed. Researchers will collect information on their medical history, nutrition, mechanical ventilation duration, and any complications like diabetic ketoacidosis or hypoglycemia. Outcomes such as time to reach target blood glucose, ventilator-free days, ICU and hospital stay lengths, and mortality rates will be evaluated. The study will last up to 28 days, with ongoing assessments to monitor patients' progress and safety.
CONDITIONS
Brief Title
Comparing Efficacy Between Two Protocols of Intravenous Insulin Infusion for Diabetic Adults in ICU
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted to hospital with a potentially life-threatening condition (critically ill patients) with HbA1C greater than 6.0
You will not qualify if you...
- Patients with diabetic ketoacidosis (DKA)
- Pregnant or breastfeeding patients
- Patients with hyperosmolar non-ketotic coma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 28 days
Participants receive intravenous insulin infusion according to one of two protocols for glycemic control while in the ICU.
Daily monitoring and adjustments during ICU stay
Duration - Up to 30 days
Participants are monitored for outcomes including ventilator-free days, ICU and hospital stay duration, and mortality for up to 30 days after treatment.
1 to 2 visits after ICU discharge depending on patient status
Trial Site Locations
Total: 1 location
1
Suez Canal University Hospitals
Ismailia, Egypt, 41522
Actively Recruiting
Research Team
A
Aiman A. Al-Touny, MD
M
Mohamed E. Abdel Ghaffar, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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