Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07008105

Comparing a Single-Session of Cognitive Behavioral Therapy, Pain Reprocessing Therapy, and Emotion Awareness and Expression Therapy for Chronic Pain

Led by Mark A. Lumley · Updated on 2025-07-15

160

Participants Needed

2

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating different single-session psychological therapies for people living with chronic musculoskeletal pain. This study compares three approaches: Cognitive Behavioral Therapy (CBT), Pain Reprocessing Therapy (PRT), and Emotion Awareness and Expression Therapy (EAET). These therapies focus on how thoughts, feelings, and brain processes influence pain, aiming to reduce or manage pain and improve functioning. The study will test which treatment works best and explore the specific ways each therapy may help. Participants will be randomly assigned to receive one 90-minute remote session of CBT, PRT, or EAET, all delivered by doctoral students in clinical psychology. A fourth group will receive treatment as usual without additional psychological therapy. These single-session interventions emphasize different aspects of pain: CBT targets changing thoughts and behaviors, PRT focuses on reducing fear of injury, and EAET addresses fear related to emotional stress. The treatments are compared against a control group over a one-month period. Participants will complete assessments of pain severity, pain interference, mood, and physical function before and after treatment, as well as at one week and one month follow-ups. Researchers will use questionnaires and rating scales to track changes in pain and emotional distress. The study aims to identify which therapy offers the most relief and understand the psychological processes behind pain improvement. Total participation involves one remote therapy session plus several brief assessments over four weeks.

CONDITIONS

Brief Title

Comparing Single-Session Therapies for Chronic Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pain for at least 3 months occurring 4 or more days per week in the past 6 months
  • Pain intensity last week is 3 or higher on a 0 to 10 scale
  • Pain interference last week is 3 or higher on a 0 to 10 scale
  • At least 18 years old
  • Lives in the United States
  • Fluent in English
  • Has a personal computer or tablet with internet access
  • Able to attend one 90-minute remote session
  • Willing to be randomly assigned to a treatment
  • Seeking to improve pain-related status through psychological therapy
Not Eligible

You will not qualify if you...

  • In past 2 years, treated for or experienced complex regional pain syndrome
  • In past 2 years, treated for or experienced epilepsy or seizure disorder
  • In past 2 years, treated for or experienced autoimmune disease
  • In past 2 years, treated for or experienced liver disease
  • In past 2 years, treated for or experienced cancer
  • In past 2 years, treated for or experienced heart disease
  • In past 2 years, treated for or experienced substance dependence or use disorder
  • In past 2 years, treated for or experienced schizophrenia or other psychotic disorder
  • In past 2 years, treated for or experienced bipolar disorder
  • In past 2 years, treated for or experienced obsessive-compulsive disorder
  • In past 2 years, treated for or experienced borderline personality disorder
  • In past 2 years, attempted or intended suicide
  • Major medical procedure scheduled within next 2 months
  • Applied for or litigating pain-related disability or worker's compensation in past year
  • Experienced major life event or stressor in past 6 months
  • Cognitive impairment with screener score 4 or less or less than or equal to 4 points on screener test
  • Unable to participate in study procedures or attend sessions as scheduled

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Outpatient Treatment

Duration - 1 session

Participants receive a single 90-minute remote session of one of three psychological therapies for chronic pain: Cognitive Behavioral Therapy, Pain Reprocessing Therapy, or Emotion Awareness and Expression Therapy. Some participants will be assigned to a no-treatment control group.

1 visit (remote)

Follow-up

Duration - 4 weeks

Participants are monitored to assess changes in pain severity, mood, and functioning at 1 week and 4 weeks after the treatment session or assignment to the control group.

2 remote follow-up assessments

Trial Site Locations

Total: 2 locations

1

Rush University Medical Center

Chicago, Illinois, United States, 60612

Actively Recruiting

2

Wayne State University

Detroit, Michigan, United States, 48202

Actively Recruiting

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Research Team

M

Mark A Lumley, PhD

M

Marjorie Heule, MS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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