Actively Recruiting
Comparing Single-Session Therapies for Chronic Pain
Led by Mark A. Lumley · Updated on 2025-07-15
160
Participants Needed
2
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many people in the US suffer from chronic pain. Often times, individuals who have chronic pain also feel depressed, anxious, or hopeless, which can worsen pain. Psychologists, therefore, have developed several treatments to help people with chronic pain. These psychological treatments differ. The most common treatment is Cognitive Behavioral Therapy (CBT) for chronic pain, which helps patients better manage pain through changing thoughts and behaviors. Two newer, less common psychological therapies are Pain Reprocessing Therapy (PRT) and Emotion Awareness and Expression Therapy (EAET). These therapies emphasize that chronic pain is mainly due to plastic processes of over-sensitization in the brain and nervous system, and that psychotherapies can significantly reduce or eliminate pain. Although similar, PRT and EAET stress different aspects of treatment. PRT emphasizes that one's fear of pain and bodily injury maintains the brain's sense of threat, thereby also maintaining the pain response; EAET emphasizes that one's conditioned psychological state of stress and tension maintains a sense of threat, thereby maintaining the pain response. These three treatments have yet to be compared; it is unclear which psychological processes are most important to treating chronic pain. There is growing interest in single-session psychotherapy interventions. Studies have shown that just a single session of CBT or EAET can help individuals reduce their pain. PRT has yet to be condensed to a single-session intervention. This study will compare a single session of CBT, PRT, and EAET with a no-treatment control group to test whether 1) one treatment outperforms the others, and 2) different mechanisms/ approaches matter to chronic pain treatment.
CONDITIONS
Official Title
Comparing Single-Session Therapies for Chronic Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pain for at least 3 months and experienced 4 or more days per week for the past 6 months
- Pain intensity last week is 3 or higher on a 0 to 10 scale
- Pain interference last week is 3 or higher on a 0 to 10 scale
- At least 18 years old
- Lives in the United States
- Fluent in English
- Has personal computer or tablet with internet access
- Able to attend one 90-minute session
- Willing to be randomized
- Seeking to improve pain through psychological therapy
You will not qualify if you...
- Treated for or experienced complex regional pain syndrome, epilepsy/seizure disorder, autoimmune disease, liver disease, cancer, heart disease, substance dependence or use disorder, schizophrenia or other psychotic disorder, bipolar disorder, obsessive-compulsive disorder, borderline personality disorder, suicide attempt or intention within past 2 years
- Major medical procedure scheduled within next 2 months
- Applied for or litigating for pain-related disability or worker's compensation in past year
- Experienced a major life event or stressor in past 6 months
- Cognitive impairment with screener score 4 or less
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Rush University Medical Center
Chicago, Illinois, United States, 60612
Actively Recruiting
2
Wayne State University
Detroit, Michigan, United States, 48202
Actively Recruiting
Research Team
M
Mark A Lumley, PhD
CONTACT
M
Marjorie Heule, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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