Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07001449

Effectiveness of the Algo(S)Therapy Pain Neuroscience Education Program Emphasizing Physiotherapists' Communication Skills in Chronic Musculoskeletal Pain: A Randomized Controlled Trial

Led by University of Thessaly · Updated on 2026-05-07

90

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the "Algo(S)Therapy" Pain Neuroscience Education (PNE) program for adults with chronic musculoskeletal pain lasting more than three months in areas such as the lumbar spine, neck, shoulder, or knee. The study aims to assess whether adding communication skills training for physiotherapists improves pain, function, and psychosocial outcomes compared to PNE alone or usual physiotherapy care. The trial follows CONSORT guidelines and includes participants aged 18 to 65 who experience moderate pain most days and speak Greek. Participants will be randomly assigned to one of three groups. The first group receives individualized PNE along with communication-focused physiotherapy delivered by trained therapists. The second group receives the same PNE intervention without additional communication training for physiotherapists. The third group receives usual physiotherapy care without any PNE or communication training. All interventions consist of ten sessions over five weeks with two sessions per week. Throughout the study, participants will complete assessments at baseline, after the intervention, and at three months follow-up. These evaluations include various measures of pain intensity, function, psychosocial factors, therapeutic alliance, and treatment satisfaction. Researchers will monitor adherence and any adverse effects electronically. The primary outcome is pain intensity measured by the Numeric Pain Rating Scale, with secondary measures assessing related physical and psychological factors.

CONDITIONS

Brief Title

Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years
  • Diagnosed with chronic musculoskeletal pain in the lumbar spine, cervical spine, shoulder, or knee
  • Pain lasting more than 3 months
  • Pain intensity of 3 or higher on the Numeric Pain Rating Scale
  • Pain present most days of the week
  • Able to understand and speak the Greek language
Not Eligible

You will not qualify if you...

  • Acute pain in any body region
  • Neurological disorders or myopathies
  • Chronic pain of non-musculoskeletal origin
  • Active cancer diagnosis
  • History of trauma, fractures, or surgery in the past year
  • Pregnancy
  • Diagnosis of fibromyalgia
  • Cognitive impairments affecting communication or questionnaire completion
  • Current use of corticosteroid medication
  • Participation in other treatment programs or alternative therapies during the study period
  • Concurrent enrollment in another clinical trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 5 weeks

Participants receive individualized Pain Neuroscience Education-based physiotherapy interventions, delivered over 5 weeks with 2 sessions per week, totaling 10 sessions. Depending on group assignment, physiotherapy includes communication skills training, only pain neuroscience education, or usual care without PNE or communication training.

2 sessions per week for 5 weeks (10 sessions total)

Follow-up

Duration - 3 months post-treatment

Participants return for assessments at 3 months after completing the treatment to evaluate pain, function, psychosocial variables, and satisfaction with treatment.

1 follow-up visit (in-person)

Trial Site Locations

Total: 1 location

1

Physiotherapy Department, University of Thessaly, Greece

Lamia, Central Greece, Greece, 35100

Actively Recruiting

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Research Team

K

Konstantina Savvoulidou

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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