Actively Recruiting
Comparative Analysis of Egyptian MTA, Biodentine, and Calcium Hydroxide as Indirect Pulp Capping Materials in Permanent Teeth A 6m Randomized Clinical Trial
Led by Cairo University · Updated on 2026-03-18
35
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing the clinical effectiveness and patient satisfaction of Egyptian MTA, Biodentine, and Calcium Hydroxide when used as indirect pulp capping materials in permanent teeth with deep carious lesions. The study focuses on vital pulp treatments, which aim to preserve the health of dental pulp by stimulating reparative dentin formation without exposing the pulp. This approach helps avoid pulp degeneration and maintains pulp vitality in teeth with deep cavities. Participants will receive one of three treatments involving different pulp capping materials: Egyptian MTA, Biodentine, or Calcium Hydroxide. All treatments begin with complete caries removal, followed by the application of the assigned material with light pressure on the deepest cavity area. A light-cured glass ionomer cement base is then applied, selective enamel etching is performed on enamel only, and a universal adhesive system is bonded on enamel and dentin. Finally, a nano hybrid composite resin is incrementally placed to restore the cavity. During the six-month study, participants will be evaluated for treatment success at one week, three months, and six months after the procedure. Researchers will assess clinical outcomes, measure pain levels, and collect patient satisfaction data at these intervals. This double-blind, randomized trial is designed to monitor oral health status and treatment effects over time, helping to determine the best pulp capping material for managing deep caries while maintaining tooth vitality.
CONDITIONS
Brief Title
Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Teeth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 22 to 45 years old
- Males or females
- Patients with vital teeth with deep carious lesions
- Patients in good general health
- Good oral hygiene
- Cooperative patients interested in participating in the study
You will not qualify if you...
- Patients with systemic diseases
- Patients with known allergic or adverse reactions to the tested materials
- Patients with poor oral hygiene
- Patients who frequently use analgesics or drugs that could mask pain
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single treatment visit
Participants receive one of three pulp capping materials (Egyptian MTA, Biodentine, or Calcium Hydroxide) applied to their permanent teeth after complete caries removal. A glass ionomer cement base and composite resin restoration are then placed.
1 visit (in-person)
Duration - 6 months
Participants return for clinical assessments of treatment success, pain, and satisfaction at 1 week, 3 months, and 6 months after treatment.
3 visits (in-person) at 1 week, 3 months, and 6 months post-treatment
Trial Site Locations
Total: 1 location
1
El Monira General Hospital
Cairo, Egypt
Actively Recruiting
Research Team
A
Alaa T Elsorogy, Master's candidate
R
Rawda H AbdElAziz
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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