Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07323043

Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia

Led by The First People's Hospital of Lianyungang · Updated on 2026-02-04

190

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled, double-blind study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or tegilidine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \<1 second; Grade IV, continuous coughing with a duration \>15 seconds.

CONDITIONS

Official Title

Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Body mass index (BMI) between 18 and 30 kg/m²
  • American Society of Anesthesiologists (ASA) grade I to III
  • Scheduled for elective surgery under general anesthesia with tracheal intubation
Not Eligible

You will not qualify if you...

  • Chronic cough lasting more than 8 weeks or asthma
  • History of allergy to drugs used in the study
  • Severe cardiovascular disease
  • Intracranial lesions
  • Eye lesions
  • Lung lesions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Affiliated Lianyungang Hospital of Xuzhou Medical University

Lianyungang, Jiangsu, China

Actively Recruiting

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Research Team

X

Xiaobao Zhang, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia | DecenTrialz