Actively Recruiting

Age: 65Years +
All Genders
ID06814054

Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Predicting Hypotension After General Anesthesia Induction in Older Adults Undergoing Elective Surgery

Led by Tanta University · Updated on 2025-07-01

189

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the ability of carotid artery corrected flow time (cFT) measured by carotid ultrasound and the inferior vena cava (IVC) collapsibility index to predict hypotension after induction of general anesthesia in elderly patients undergoing elective surgery. Hypotension after anesthesia induction is common and can lead to serious organ damage, especially in older adults who are more sensitive to blood pressure changes due to heart and vascular conditions. The study involves non-invasive ultrasound measurements taken shortly before anesthesia induction. The cFT is measured on the right common carotid artery using a linear probe, while the IVC collapsibility index is assessed using a subcostal ultrasound approach during spontaneous breathing. Blood pressure and heart function will be closely monitored after anesthesia induction. If hypotension occurs, defined by specific blood pressure drops, fluid boluses and medication may be given as needed. Participants will undergo ultrasound imaging before surgery and have their blood pressure monitored closely for 15 minutes after intubation. Researchers will assess how well these ultrasound measurements predict hypotension during this period. The main outcome is the diagnostic accuracy of cFT and IVC collapsibility in predicting low blood pressure immediately before anesthesia induction. Safety and response to treatment will also be recorded until surgery ends. Total participation lasts from preoperative assessment through anesthesia and surgery.

CONDITIONS

Brief Title

Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 65 years or older
  • American Society of Anaesthesiologists Physical Status I to II
  • Scheduled for elective surgery under general anesthesia
  • Fasted for at least 6 to 8 hours before surgery
Not Eligible

You will not qualify if you...

  • Patients who refuse to participate in the study
  • American Society of Anaesthesiologists Physical Status III or higher
  • History of peripheral arterial diseases or atherosclerosis
  • Body mass index greater than 30 kg/m2
  • Arrhythmia or cardiomyopathy
  • Chronic obstructive pulmonary disease (COPD)
  • Baseline systolic arterial pressure of 180 mmHg or higher, or less than 90 mmHg
  • Any episode of desaturation or difficult intubation during anesthesia induction

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Approximately 10 minutes before anesthesia induction

Participants undergo ultrasound measurements including Carotid Artery Corrected Flow Time and Inferior Vena Cava collapsibility index before induction of general anesthesia to predict hypotension.

1 visit (in-person)

Monitoring

Duration - From induction of anesthesia through 15 minutes post-intubation

Participants are monitored for blood pressure changes from anesthesia induction until 15 minutes after endotracheal intubation to observe for hypotension and manage it if it occurs.

Continuous monitoring during surgery preparation and induction

Trial Site Locations

Total: 1 location

1

Faculty of medicine, Tanta university

Tanta, El Gharbyia, Egypt, 31111

Actively Recruiting

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Research Team

T

tarek AH Mostafa

S

sameh Ahmed

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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