Actively Recruiting

Age: 18Years +
All Genders
NCT07496723

Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis

Led by Sanliurfa Education and Research Hospital · Updated on 2026-04-01

200

Participants Needed

1

Research Sites

45 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Acute appendicitis is one of the most common surgical emergencies, but diagnostic uncertainty may still lead to unnecessary appendectomy in some patients. This prospective observational study aims to evaluate the diagnostic performance of computed tomography (CT) reporting and the Appendicitis Inflammatory Response (AIR) score in adult patients undergoing appendectomy for suspected acute appendicitis. The primary objective is to determine the negative appendectomy rate based on final histopathology. Secondary objectives are to assess the agreement between AIR score, CT findings, intraoperative severity grading, and pathology results, and to explore diagnostic performance across patient subgroups. No study-specific intervention beyond routine clinical care will be performed.

CONDITIONS

Official Title

Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Presenting to the emergency department with suspected acute appendicitis
  • Underwent computed tomography after clinical evaluation
  • CT report compatible with acute appendicitis
  • Underwent appendectomy for presumed acute appendicitis
  • Provided informed consent
Not Eligible

You will not qualify if you...

  • Younger than 18 years
  • Pregnancy
  • Planned additional surgical intervention in the same session for a reason other than appendicitis
  • Intraoperative finding of non-appendiceal pathology requiring different surgery
  • Refusal to participate in the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Sanliurfa Education and Research Hospital

Sanliurfa, Şanlıurfa, Turkey (Türkiye)

Actively Recruiting

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Research Team

V

Vedat Kaplan, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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