Prospective Evaluation of CT Reporting and AIR Score Impact on Negative Appendectomy Rates in Adults With Acute Appendicitis

What this Trial Is About

Researchers are evaluating the diagnostic accuracy of computed tomography (CT) reporting and the Appendicitis Inflammatory Response (AIR) score in adults suspected of having acute appendicitis who undergo appendectomy. The study aims to measure how often appendectomies are performed unnecessarily, based on final pathology results. It also examines how well the AIR score, CT findings, and surgical severity grading agree with pathology, and explores these diagnostics across different patient groups. This prospective observational study includes adults 18 years and older who visit the emergency department with suspected appendicitis, receive a CT scan showing signs of appendicitis, and then have an appendectomy. No extra treatments or interventions apart from standard care are performed. Clinical, demographic, and diagnostic data including laboratory results, CT reports, and surgical findings are collected and analyzed. Participants will have their clinical data recorded, including symptom details, lab tests, and imaging results. Researchers will compare CT reports, AIR scores, and surgical grades to final pathology findings within 30 days after surgery. The main measurement is the rate of negative appendectomies. Data is collected confidentially, with no study procedures beyond routine care, and the study is expected to end by January 2027.

Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis