Study of CT Scan and AIR Score Impact on Negative Appendectomy in Adults
Undergoing Surgery for Suspected Acute Appendicitis
Led by Sanliurfa Education and Research Hospital · Updated on 2026-04-01
200
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the diagnostic accuracy of computed tomography CT reporting and the Appendicitis Inflammatory Response AIR score in adults suspected of having acute appendicitis who undergo appendectomy. The study aims to measure how often appendectomies are performed unnecessarily, based on final pathology results. It also examines how well the AIR score, CT findings, and surgical severity grading agree with pathology, and explores these diagnostics across different patient groups.
This prospective observational study includes adults 18 years and older who visit the emergency department with suspected appendicitis, receive a CT scan showing signs of appendicitis, and then have an appendectomy. No extra treatments or interventions apart from standard care are performed. Clinical, demographic, and diagnostic data including laboratory results, CT reports, and surgical findings are collected and analyzed.
Participants will have their clinical data recorded, including symptom details, lab tests, and imaging results. Researchers will compare CT reports, AIR scores, and surgical grades to final pathology findings within 30 days after surgery. The main measurement is the rate of negative appendectomies. Data is collected confidentially, with no study procedures beyond routine care, and the study is expected to end by January 2027.
CONDITIONS
Brief Title
Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis
Research Team
V
Vedat Kaplan, MD
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Presentation to the emergency department with suspected acute appendicitis
Underwent computed tomography after clinical evaluation
Computed tomography report compatible with acute appendicitis
Underwent appendectomy for presumed acute appendicitis
Provided informed consent
You will not qualify if you...
Age younger than 18 years
Pregnancy
Planned additional surgical intervention in the same session for a reason other than appendicitis
Intraoperative finding of a non-appendiceal pathology requiring a different surgical procedure
Refusal to participate in the study
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) in the emergency department
Diagnostic Evaluation
Duration - Less than 1 day
Participants undergo computed tomography (CT) as part of routine emergency care to evaluate suspected acute appendicitis and clinical data including the Appendicitis Inflammatory Response (AIR) score are collected.
1 visit (in-person) in the emergency department
Surgery
Duration - 1 day
Participants undergo appendectomy based on clinical and CT findings as part of routine care.
1 visit (in-person) for surgery
Post-operative Follow-up
Duration - Up to 30 days
Participants are observed up to 30 days post-surgery during which final pathology reports and intraoperative grading are assessed.
Follow-up visits as per routine clinical care
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Negative appendicectomy rate as a quality metric in the management of appendicitis: impact of computed tomography, Alvarado score and the definition of negative appendicectomy.