Comparison of Double-tract Reconstruction and Tubular Gastric Anastomosis for Proximal Gastric Cancer Surgery Evaluating Postoperative Reflux and Quality of Life

What this Trial Is About

Researchers are studying patients with proximal gastric cancer, specifically those with Siewert type II or III tumors at clinical stages cT1-3N0-1M0. The study compares two surgical methods, double-tract reconstruction and tubular gastric anastomosis, to evaluate their effects on postoperative outcomes including reflux esophagitis and quality of life. This research is conducted across six tertiary hospitals with randomized group assignments. Participants undergo radical proximal gastrectomy followed by either double-tract reconstruction or tubular gastric anastomosis, depending on their assigned group. The interventions are surgical procedures aimed at restoring digestive tract continuity. The study collects data on postoperative reflux using gastroscopy and 24-hour esophageal pH monitoring, alongside rating scales to assess severity and impact. During the study, participants are monitored for reflux esophagitis incidence and severity six months after surgery. Nutritional recovery is also assessed one year postoperatively. Researchers review electronic medical records and conduct scheduled examinations to measure outcomes. The total study duration includes preoperative assessment, surgery, and follow-up evaluations extending up to one year after surgery.

Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer