Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT07287761

Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting

Led by Ankara Education and Research Hospital · Updated on 2025-12-17

60

Participants Needed

1

Research Sites

25 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Coronary Artery Bypass Grafting (CABG) is a common surgical procedure for ischemic heart disease, but it often leads to severe acute and chronic postoperative pain, which can delay recovery and reduce patient comfort. Effective pain management is crucial to prevent pulmonary complications and long hospital stays. Peripheral nerve blocks are increasingly used to reduce opioid consumption and improve patient satisfaction after major surgery. This prospective, observational study aims to compare the effectiveness and safety of two different regional anesthesia techniques, the Erector Spinae Plane Block (ESPB) and the Serratus Posterior Superior Intercostal Plane Block (SPSIPB), in managing postoperative pain in patients undergoing CABG via median sternotomy. Patients aged 18-80 years, classified as ASA II-III, who are scheduled for elective CABG will be included. The choice of block technique (ESPB or SPSIPB) will be determined by the operating anesthesiologist based on the visibility of anatomical structures (transverse processes) under ultrasound guidance. All patients will receive the same general anesthesia and be managed postoperatively with Intravenous Patient-Controlled Analgesia (PCA). The main goal is to determine which block provides optimal pain control, measured by the time to first rescue analgesia and pain scores (NRS) at various time points after extubation. Secondary outcomes include intraoperative opioid consumption, total PCA usage, extubation time, and the incidence of opioid-related side effects. The findings will help optimize pain protocols for cardiac surgery patients.

CONDITIONS

Official Title

Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for elective Coronary Artery Bypass Grafting (CABG) via median sternotomy
  • Age between 18 and 80 years
  • Classified as American Society of Anesthesiologists (ASA) Physical Status Class II or III
  • Provided written and verbal informed consent to participate
Not Eligible

You will not qualify if you...

  • Not providing consent
  • Age over 80 years or ASA Physical Status Class greater than III
  • Unable to understand the Numerical Rating Scale (NRS) or having communication difficulties
  • Known coagulation or bleeding disorders
  • Skin infection at the site for peripheral nerve block
  • Morbid obesity with Body Mass Index (BMI) over 35 kg/m2
  • Chronic pain, opioid or substance dependence, or use of chronic analgesics
  • Known allergy to local anesthetics
  • Liver or kidney function disorders
  • History of previous median sternotomy surgery
  • Emergency surgery planned

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ankara Training and Research Hospital

Ankara, Altındag, Turkey (Türkiye), 06230

Actively Recruiting

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Research Team

A

Abdullah KONAN, M.D

CONTACT

S

Suna AKIN TAKMAZ, M.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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