Actively Recruiting
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar: Assessment of Post-operative Sequelae
Led by Amerigo Giudice · Updated on 2025-01-16
22
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how piezoelectric surgery compares with the traditional surgical method for removing lower third molars in patients aged 14 to 24. The study focuses on the effects of these two techniques on soft tissue swelling after the procedure. Facial swelling after surgery will be measured using a photogrammetry facial scanner to assess differences in recovery. Participants will undergo bilateral germectomy of the lower third molars using either the piezoelectric technique or the traditional surgical method. These two approaches are compared to see how they affect postoperative swelling. The study uses a randomized design with triple masking to assign participants to one of these two surgical methods. During the study, facial swelling will be measured before surgery and then again at 2 and 7 days after surgery using qualitative and quantitative analyses, including volumetric and linear measurements. Secondary outcomes include assessing jaw movement limitations (trismus) and pain levels with a visual analogue scale over the same time points. Participants are followed for a short period post-surgery to monitor these outcomes.
CONDITIONS
Brief Title
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged between 14 and 24 years
- Both lower third molars are in the developmental stage with incompletely formed roots
- Both lower third molars require extraction for prophylactic, therapeutic, or strategic reasons
- Good quality radiographic investigations (CBCT) are available
- Good general health status
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 7 days after each surgery
Participants undergo bilateral germectomy of mandibular third molars using either the piezoelectric or traditional surgical technique as part of a crossover design. Post-operative swelling and pain are assessed.
1 surgery visit followed by 2 post-operative visits at 2 days and 7 days after surgery
Trial Site Locations
Total: 1 location
1
Magna Graecia University of Catanzaro
Catanzaro, Italy, 88100
Actively Recruiting
Research Team
A
Amerigo Giudice, Prof, MD, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here