Actively Recruiting

Phase 2
Age: 0Days - 28Days
All Genders
NCT07102836

COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY

Led by Quaid-e-Azam Medical College · Updated on 2025-08-05

110

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.

CONDITIONS

Official Title

COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY

Who Can Participate

Age: 0Days - 28Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Term or near-term newborns
  • Age less than 7 days at enrollment
  • Bilirubin levels within phototherapy range according to NICE bilirubin threshold charts
  • No identifiable pathology
  • Tolerating oral feeds
  • Written informed consent from parent or guardian
Not Eligible

You will not qualify if you...

  • Positive sepsis screen or clinical signs of infection
  • Direct hyperbilirubinemia
  • Gastrointestinal malformations
  • Oral intolerance
  • Requiring mechanical ventilation
  • Congenital anomalies
  • Parent or guardian refusal to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sadiq Abbasi Hospital, QAMC, Bahawalpur

Bahawalpur, Punjab Province, Pakistan, 63100

Actively Recruiting

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Research Team

M

Malik M. Umair Fazal, MBBS, FCPS Paediatrics

CONTACT

D

Dr. Muhammad Anwar, MBBS, FCPS Neonatology

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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