Actively Recruiting
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2025-09-08
500
Participants Needed
1
Research Sites
246 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective of this study is to generate diagnosis and therapeutic-decision tools through the identification of molecular causes of PIDs with autoimmunity/inflammation and the variability in disease outcome at the transcriptional level using a combination of omics signatures (transcriptomics, epigenomics, proteomics, metagenomics, metabolomics and lipidomics).
CONDITIONS
Official Title
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals under 18 years old
- Weigh more than 6 kg (controls) or more than 9 kg (patients)
- No immune-related disease or cancer (controls)
- Patients treated at Necker hospital with PIDs and autoimmunity/inflammation related to known genetic defects
- Patients with health insurance
- Parents have signed informed consent
You will not qualify if you...
- Use of antibiotics within 2 weeks before inclusion
- Lack of consent from parent or child
- Receiving cytotoxic cancer treatments
- Receiving antiviral treatments (e.g., for HIV, hepatitis)
- Short-term life-threatening conditions
- Individuals under judicial protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
hôpital Necker Enfants Malades
Paris, France
Actively Recruiting
Research Team
F
Frédéric Rieux-Laucat
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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