Trigger Finger

Researchers are studying pain management methods for patients undergoing shoulder surgery, a common orthopedic procedure often linked with moderate to severe pain after surgery. The study compares two nerve block techniques the standard interscalene brachial plexus block, which can cause breathing difficulties due to unintended nerve effects, and a newer diaphragm-sparing method combining suprascapular and axillary nerve blocks. The goal is to assess pain relief and preserve respiratory function during recovery. Participants will receive one of two ultrasound-guided nerve block procedures before surgery. One group will have an interscalene block with 10 mL of 0.5% bupivacaine injected near the C5 and C6 nerve roots. The other group will receive a combination of suprascapular and axillary nerve blocks, each with 5 mL of 0.5% bupivacaine injected around specific nerves near the shoulder. Both procedures are designed to provide pain relief while minimizing breathing complications. During the study, participants pain intensity at rest and movement will be measured up to 24 hours after surgery, along with total opioid consumption. Respiratory function will be monitored by measuring diaphragmatic movement and lung volumes before and after the nerve blocks and throughout the perioperative period. The study includes adult patients aged 18 to 65 scheduled for elective arthroscopic shoulder surgery, with assessments focused on pain control and breathing safety.

Researchers are investigating upper-extremity proprioception impairment in patients experiencing radicular neuropathic symptoms caused by cervical disc herniation. This study focuses on the specific subgroup of cervical radiculopathy, which has not been systematically examined before, aiming to better understand the relationship between proprioceptive deficits and clinical outcomes such as pain and functional status. The study compares patients aged 18 to 65 years with cervical radiculopathy to a healthy control group matched by age, sex, and body mass index. Proprioception is assessed using the PRO-Reach method, which measures multisensory spatial representation of the entire upper limb through multiplanar and multi-joint evaluations without the need for computerized or robotic devices. Participants undergo baseline assessments including the Upper Limb Proprioception Reaching Test PRO-Reach, pain rating scales Numeric Rating Scale and DN-4 Questionnaire, quality of life evaluation SHORT FORM-12, handgrip strength testing, and disability questionnaires Quick Disabilities of the Arm, Shoulder and Hand Questionnaire. These measures help researchers evaluate sensory-motor function and its impact. The study involves healthy volunteers and patients, with data collection focused on initial measurements before any treatments, and participation is expected to last during the baseline assessment period.

This research aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in adults with trigger finger, a condition causing pain, clicking, and locking of the finger due to tendon entrapment. While corticosteroid injections like betamethasone are commonly used first-line treatments, they can have side effects. Dextrose injections are being studied as a possible alternative that may help tissue healing, but evidence for their effectiveness in trigger finger is limited. Participants will be randomly assigned to receive one of two ultrasound-guided injections at the A1 pulley either 1 ml lidocaine with 1 ml betamethasone or 1 ml lidocaine with 1 ml 30% dextrose solution diluted to 15% dextrose. All injections are performed under sterile conditions. The study uses a triple-blind design where the injector, participant, and assessor are unaware of the treatment given. Participants will be assessed at baseline, 1 hour, 2 weeks, 4 weeks, and 12 weeks after injection. Researchers will measure pain intensity using the Numeric Rating Scale as the primary outcome. Secondary outcomes include severity of triggering, hand function, grip and pinch strength, and fine motor skills. These evaluations aim to determine whether dextrose injections can serve as a safe and effective alternative to corticosteroids for treating trigger finger.

Breast cancer is one of the most common cancers affecting women worldwide, responsible for a significant number of cancer cases and deaths. Advances in screening and treatment have improved survival rates, but many women experience side effects after treatment, including upper limb dysfunction and lymphoedema, which can impact daily activities and quality of life. This study aims to explore how combined upper extremity aerobic and resistance exercise training, compared to aerobic exercise alone, affects arm exercise capacity, muscle strength, arm functionality, sarcopenia, frailty, quality of life, and lymphoedema in breast cancer patients. Participants will be randomly assigned to one of two groups one group will engage in a 12-week program of upper extremity aerobic exercise training with sessions three times a week lasting 25 minutes each, while the other group will receive the same aerobic exercise combined with progressive resistance training using elastic resistance bands gradually increased over 12 weeks. The study will assess the effects of these exercise programs on various physical and health outcomes related to breast cancer treatment side effects. During the study, participants will be evaluated over one year, including tests such as the 6-minute Pegboard and Ring Test and measures of maximal arm exercise capacity. Researchers will also assess quality of life, peripheral muscle strength, arm functionality, sarcopenia, frailty, lymphoedema, and other health parameters. This monitoring will help determine how the exercise programs influence recovery and physical function after breast cancer treatment.

Researchers are studying trigger finger, a condition affecting finger movement, in adults aged 18 to 75 years. The study aims to compare the effects of three different treatments a static finger splint, paraffin bath therapy, and peloidotherapy, all combined with home exercise programs. Patients with specific grades of trigger finger will be included, and the study is designed as a prospective, randomized, controlled trial with blinded assessments to evaluate treatment outcomes. Participants will be randomly assigned to one of three groups. One group will use a static finger splint that blocks the proximal interphalangeal joint continuously for 6 weeks, combined with home exercises. The second group will receive paraffin bath therapy for 20 minutes daily over 15 sessions within 3 weeks plus home exercises. The third group will undergo peloidotherapy at 45C for 20 minutes daily over 15 sessions within 3 weeks, also combined with home exercises. All patients will receive education about the disease and activity modifications. Participants will be evaluated at the start, after 3 weeks, and after 6 weeks. Assessments include pain intensity using a visual analog scale, trigger finger severity by Greens classification, hand function via the Michigan Hand Outcomes Questionnaire, patient global improvement, and ultrasound measures of tendon and pulley thickness and effusion. Compliance with splint use and exercises will be monitored, and any treatment side effects will be recorded. Patients will avoid analgesic or anti-inflammatory medications during the study and prior to assessments.

Researchers are comparing two methods of infraclavicular brachial plexus block, a type of peripheral nerve block used for anesthesia and pain relief in patients undergoing forearm and hand surgeries. This study focuses on patients with obesity BMI over 30 who require regional anesthesia for surgery and aims to evaluate differences between the conventional and retroclavicular approaches. During the study, participants will be randomly assigned to receive either the conventional or retroclavicular approach to the infraclavicular block. Both methods use the same local anesthetic mixture of 20 ml 0.5% bupivacaine plus 5 ml 2% lidocaine, administered under ultrasound guidance while patients lie in a supine position. The main focus is to measure the time taken to perform the block, along with secondary outcomes such as pain scores up to 24 hours after surgery and patient satisfaction one day after. Participants will be monitored during and after the procedure, with assessments including pain evaluations and satisfaction surveys. The study is quadruple-masked and randomized to ensure unbiased comparison. Researchers will measure block performance time and follow patients pain and satisfaction for 24 hours postoperatively. The study runs from September 2025 through June 2026 and involves adult patients aged 18 to 80 years with specific anesthesia suitability and health status criteria.

This research aims to evaluate how effective a nighttime extension orthosis is after receiving a cortisone injection for treating trigger finger, also known as stenosing flexor tenosynovitis. The goal is to see if wearing the orthosis improves pain relief and hand function compared to not wearing one, at 12 weeks after the injection. The study is a randomized controlled trial focusing on these outcomes in adults with trigger finger. Participants are divided into two groups. The experimental group receives a cortisone injection and is fitted with a proximal interphalangeal joint PIPJ extension night orthosis called the Oval-8, which they wear at night for six weeks. The control group receives the cortisone injection but does not use the orthosis and is advised to move their fingers normally. Both groups have follow-up contact at six and twelve weeks to record symptom resolution, pain levels, and functional scores. During the study, participants will have assessments of their pain using the Visual Analogue Scale VAS, functional ability via the QuickDASH questionnaire, and the timing of symptom resolution. These measures will be collected during follow-up phone calls or emails at six and twelve weeks after the injection. The study is sponsored by Cedars-Sinai Medical Center and will continue monitoring outcomes until May 2026.

Researchers are evaluating the effectiveness of two common treatments for Trigger Finger TF, a condition also known as Stenosing Tenosynovitis. This study compares Extracorporeal Shock Wave Therapy ESWT and splint therapy, aiming to understand which approach is more effective for managing TF symptoms. The trial is a randomized controlled prospective study involving adult patients diagnosed with stage 1 or stage 2 trigger finger. Participants are randomly assigned to one of three groups ESWT alone, splint therapy alone, or a combination of ESWT and splint therapy. ESWT is applied to the A1 pulley at 15 Hz with 1000 shock wave impulses and 2.0 bar pressure, administered in five weekly sessions. The splint therapy involves using a trigger finger splint that immobilizes the metacarpophalangeal MCP joint, which participants are asked to wear throughout the day for eight weeks. Evaluations occur before treatment, immediately after eight weeks of treatment, and four weeks post-treatment at twelve weeks. Participants will undergo assessments including pain intensity measured by a visual analog scale, grip and pinch strength, number of triggering events, functional assessments, and treatment satisfaction. These evaluations take place at baseline, at the end of treatment 8 weeks, and four weeks after treatment ends 12 weeks. The study includes 54 participants, with 18 in each group, and aims to monitor treatment effects and satisfaction over a total follow-up of approximately three months.

Researchers are evaluating the effects of biofeedback-guided training compared to conventional therapy on muscle strength and postural alignment in adults with Upper Cross Syndrome UCS. This condition, often caused by prolonged poor posture and repetitive movements, leads to muscle imbalances, neck and upper back pain, and postural deviations like forward head posture and increased thoracic kyphosis. The study aims to assess which approach better improves muscle strength and posture in UCS patients aged 25 to 45 years. Participants are randomly assigned to one of two groups Group A receives biofeedback-guided strength training targeting deep cervical flexors, rhomboids, and trapezius muscles using a biofeedback pressure unit at different pressure levels, combined with a warm-up hot pack. Group B receives conventional therapy involving hot pack application and a structured exercise program including chin tucks, scapular squeezes, and pectoral stretches. Both groups undergo 12 sessions over 4 weeks, with three sessions per week. During the study, participants are assessed at baseline, after the first session, and weekly thereafter using standardized measures such as the cranio-cervical flexion test, neck pain rating scale, neck disability index, and cervical range of motion tests. Researchers monitor changes in muscle strength, postural alignment, pain levels, and neck function. The total study participation lasts four weeks, with careful tracking of symptoms and functional improvements to compare the two intervention methods.

Researchers are evaluating the effectiveness and safety of a minimally invasive procedure called ultrasound-guided tri-directional needle knife release for patients with trigger finger who have not improved with conservative treatments. Trigger finger occurs due to thickening of the A1 pulley, causing pain, stiffness, and limited hand movement. This study focuses on improving hand function, reducing pain, increasing finger mobility, and overall patient satisfaction. The procedure uses ultrasound guidance for precise and safe dissection of the thickened A1 pulley under local anesthesia with lidocaine and bupivacaine. The device used is the Sonosite M-Turbo Ultrasound Machine with a linear probe for real-time imaging. This treatment aims to minimize risks and improve recovery compared to conventional methods. Participants will be monitored over six months to assess improvements in hand and finger function, pain levels, and finger mobility. Researchers will also track patient satisfaction and any complications related to the procedure. Follow-up visits will ensure proper recovery and evaluate treatment outcomes throughout this period.