Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT06575712

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

Led by Duke University · Updated on 2026-04-09

177

Participants Needed

1

Research Sites

175 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.

CONDITIONS

Official Title

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Receipt of an autologous hematopoietic stem cell transplant or CAR-T cell therapy for hematologic malignancy such as leukemia, lymphoma, or multiple myeloma
  • Age over 18 years
  • Self-reported fatigue, pain, and psychological distress with at least two symptoms rated above 3 on a 0-10 scale
  • Life expectancy greater than 12 months
Not Eligible

You will not qualify if you...

  • Cognitive impairment such as dementia recorded or suspected
  • Brain metastases
  • Severe psychiatric conditions like psychotic disorders that prevent safe participation
  • Inability to converse in English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Duke Cancer Institute

Durham, North Carolina, United States, 27705

Actively Recruiting

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Research Team

A

Allison Diachina

CONTACT

S

Sarah Kelleher, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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