Actively Recruiting
Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults
Led by Shanghai 6th People's Hospital · Updated on 2026-04-23
60
Participants Needed
2
Research Sites
308 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention and treatment of stroke. In recent years, stroke in young adults has an increasing incidence and a considerable socioeconomic impact because of high disability rate and health-care costs. So there is an urgent need to explore the role and mechanism of intestinal microecology imbalance in stroke, especially in the development and prognosis of stroke in young people. This study aims to use multi-omics technologies, including microbial diversity, metagenomics and metabonomics, to reveal the characteristics of intestinal flora in young stroke patients, identify biomarkers for predicting outcome after stroke and early detection of young people at high risk of stroke, and to further explore the role of gut-brain axis in the pathogenesis of stroke.
CONDITIONS
Official Title
Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of acute ischemic or hemorrhagic stroke
- Admission within 12 hours of stroke onset
- Aged 18 to 45 years
You will not qualify if you...
- History of neurological diseases, myocardial infarction, kidney or liver abnormalities, or metabolic diseases
- Presence of tumors, inflammatory bowel disease, or other digestive system diseases
- Serious life-threatening diseases or conditions
- Antibiotics, probiotics, or prebiotic treatment within the past 3 months
- Patients who deteriorate and die before fecal sample collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Shanghai 6th People's Hospital
Shanghai, China, 200233
Not Yet Recruiting
2
Shanghai 6th People's Hospital
Shanghai, China, 200233
Actively Recruiting
Research Team
H
Hao Chen, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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