Study of Intestinal Microecology Imbalance and Its Impact on Risk and Recovery from Stroke in Young Adults Aged 18 to 45

What this Trial Is About

Researchers are investigating the connection between imbalances in gut bacteria and stroke in young adults, a growing concern due to its rising incidence and significant impact on health and society. This observational study aims to explore how changes in intestinal microecology may influence the development and outcomes of stroke in people aged 18 to 45 years. The research uses advanced methods to analyze gut microbiota diversity and related biological markers to better understand stroke mechanisms and identify early risk factors in young patients. The study includes three groups young adults who experienced their first acute ischemic stroke within 12 hours, those with their first acute hemorrhagic stroke within the same timeframe, and healthy young controls. By comparing these groups, researchers hope to identify specific gut flora patterns linked to stroke risk and prognosis. The study will apply multi-omics technologies such as metagenomics and metabonomics to achieve these goals. Participants will be monitored with assessments including the Modified Rankin Scale at 3 months after stroke to evaluate recovery and outcomes. Stool samples will be collected to analyze gut bacteria and metabolites. The research team will also collect clinical data to investigate the gut-brain axiss role in stroke. The study will continue until December 2027, with healthy volunteers also included for comparison.

Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults