Study on Clinical Features and Kidney Tissue Changes in Adults with Type 2 Diabetic Nephropathy

What this Trial Is About

Type 2 diabetes mellitus is the leading cause of end-stage renal disease due to diabetic nephropathy. This research investigates the differences between diabetic nephropathy DN and non-diabetic renal diseases NDRD in people with type 2 diabetes. The study aims to clarify the clinical and pathological features of type 2 diabetic kidney disease and develop criteria for clinical staging and prognosis since current staging is based on type 1 diabetic nephropathy. Participants will be grouped based on pathological results and clinical features such as kidney function and protein levels in urine. The study involves a long-term observation where the cohort will be followed for at least 10 years to analyze the correlation between clinical features and pathology. No treatments or interventions are provided as this is an observational study. Participants will be monitored through assessments of kidney function, specifically looking at changes in estimated glomerular filtration rate eGFR and urine protein over 24 months. Researchers will collect clinical data, including renal biopsy results and proteinuria levels, to evaluate disease progression. The study continues to track participants for outcomes related to kidney health over the extended follow-up period.

Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy