Actively Recruiting

Age: 18Years +
All Genders
NCT03865914

Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy

Led by Chinese PLA General Hospital · Updated on 2022-03-31

2000

Participants Needed

1

Research Sites

682 weeks

Total Duration

On this page

Sponsors

C

Chinese PLA General Hospital

Lead Sponsor

B

Beijing Municipal Science & Technology Commission

Collaborating Sponsor

AI-Summary

What this Trial Is About

With the rapid increase of diabetic nephropathy worldwide, type 2 diabetes mellitus(DM) is the leading cause of end-stage renal disease(ESRD). Pathological types of diabetic kidney disease(DKD) could be mainly divided into diabetic nephropathy(DN)and non-diabetic renal diseases(NDRD). There are no accurate renal biopsy indications and standardized operation procedures for type 2 diabetic nephropathy. The clinical stages of type 2 diabetic nephropathy still referred to the Mogensen stage of type 1 diabetic nephropathy. Thus, our study aim to clarify the differences in clinical phenotype between type 2 DN and type 2 NDRD, analysis the correlation between clinical and pathological features, and offer the criteria for clinical staging and prognosis.

CONDITIONS

Official Title

Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older, male or female
  • Clinically diagnosed with type 2 diabetes mellitus
  • Presence of kidney impairment including microalbuminuria, overt proteinuria, or renal insufficiency
  • Completed renal biopsy with full pathological diagnosis
  • Signed informed consent obtained from patients
Not Eligible

You will not qualify if you...

  • Incomplete medical history
  • Diagnosis of other secondary kidney diseases
  • Presence of hereditary kidney disease
  • Autoimmune diseases
  • Malignant tumors with life expectancy less than 6 months
  • Pregnancy or lactation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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+1

Trial Site Locations

Total: 1 location

1

Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853

Actively Recruiting

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Research Team

X

Xiangmei Chen, MD.&Ph.D

CONTACT

Z

Zheyi Dong, MD.&Ph.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy | DecenTrialz