Actively Recruiting
Cost Effective Air Filtration Intervention and Particulate Matter Monitoring in Low-Income Housing to Reduce Asthma Morbidity
Led by Columbia University · Updated on 2026-06-02
55
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
L
Little Sisters of the Assumption Family Health Service
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma symptoms in children aged 7 to 18 years living in low-income housing in East Harlem, New York City. This intervention study is conducted over a two-year period and aims to reduce airborne particulate matter exposure, airway inflammation, and asthma morbidity in this high-risk population. The trial is based on previous research showing the potential benefits of home air cleaners in similar communities. Participants will receive a single Austin Air Cleaner, a device with multiple filters including a medical grade HEPA filter, designed to reduce indoor air pollution. This single-arm study lasts one year, during which the air cleaner is placed in the child's home. The device continuously monitors particulate matter levels before and after installation. Participants serve as their own controls, with air quality and health outcomes compared before and after the intervention. Throughout the study, researchers will measure lung function and airway inflammation using pulmonary function tests and fractional exhaled nitric oxide (FeNO) tests at multiple time points before and after the air cleaner is turned on. Asthma symptoms, including wheezing attacks and emergency department visits, will be tracked monthly for a year. The study also includes questionnaires to assess symptom changes and incentives to encourage compliance with using the air cleaner. The total participation duration for each child is one year.
CONDITIONS
Brief Title
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 7-18 years
- Asthma symptoms in the past 4 weeks
- Resident in lower-income housing in NYC Northern Manhattan and South Bronx
You will not qualify if you...
- Inability to successfully perform spirometry maneuver or FeNO test
- Family planning to move in the next year
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 year
Participants receive a HEPA air cleaner installed in their home to reduce air pollutants exposure and asthma symptoms.
1 baseline visit and monthly visits for up to 12 months
Trial Site Locations
Total: 1 location
1
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
M
Matthew S Perzanowski, PhD
L
Luis M Acosta, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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